Results 211 to 220 of about 1,830,234 (387)

‘The System Can't Cope’: The Service System Response to Alcohol and Other Drug‐Facilitated Sexual Violence

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Alcohol and other drug‐facilitated sexual violence can have significant impacts on victim‐survivors, yet little is known about what support service providers offer them. To understand the experiences and perceptions of service providers, interviews with counsellors, health workers, forensic toxicologists and harm reduction workers were ...
Jessica Ison   +5 more
wiley   +1 more source

Effects of Dictyophora polysaccharide on cerebellar Purkinje cell degeneration in a chronic alcohol mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang   +5 more
wiley   +1 more source

Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system

open access: yesCell Reports
Summary: High-intensity alcohol drinking during binge episodes contributes to the socioeconomic burden created by alcohol use disorders (AUDs), and nociceptin receptor (NOP) antagonists have emerged as a promising intervention.
Harold Haun   +9 more
doaj  

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

Legacy from the Transition?: Alcohol Consumption by Young Adults in Ukraine [PDF]

open access: yes
The study analyses the effects of transition on the amount and patterns of alcohol consumption. We test the hypothesis of how far negative experiences induced by the collapse of the Soviet Union have led to drinking in the young generation of Ukrainians.
Alexandra Avdeenko   +2 more
core  

Acute Renal Failure after Binge Drinking of Alcohol and Nonsteroidal Antiinflammatory Drug Ingestion.

open access: bronze, 1997
Nobuo Tsuboi   +6 more
openalex   +2 more sources

Association between ALDH2 and ADH1B polymorphisms, alcohol drinking and gastric cancer: a replication and mediation analysis

open access: yesGastric Cancer, 2018
Kuka Ishioka   +9 more
semanticscholar   +1 more source

Establishment of a patient‐derived drug‐resistant oral squamous cell carcinoma animal model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Patient‐derived xenograft (PDX) tissues from less‐responsive groups (larger tumors) were serially passaged. Sequential passaging and drug exposure in PDX models recapitulated clinical tumor evolution, enabling the development of drug‐resistant oral squamous cell carcinoma (OSCC) models. This study can offer methodological insights for precision therapy
Chuanni Feng   +8 more
wiley   +1 more source

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