Results 211 to 220 of about 614,273 (365)

Clinical Validation of Reduced Alcohol Consumption After Treatment for Alcohol Dependence Using the World Health Organization Risk Drinking Levels [PDF]

, 2016
Katie Witkiewitz, Kevin A. Hallgren, Henry R. Kranzler, Karl Mann, Deborah S. Hasin, Daniel E. Falk, Raye Z. Litten, Stephanie S. O’Malley, Raymond F. Anton   +8 more
openalex   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Alcohol drinking patterns

, 2006
This thesis is based on studies conducted in the period from 2003 to 2006 at Center for Alcohol Research, the National Institute of Public Health in cooperation with the Department of Clinical Biochemistry, Herlev University Hospital. Obtained results are presented in four scientific papers three of which are published, and one is submitted.Main ...
openaire   +1 more source

Dutch and Norwegian Support of Alcohol Policy Measures to Prevent Young People from Problematic Drinking: A Cross-National Comparison [PDF]

, 2012
R. van der Sar, Elisabet E. Storvoll, Evelien Brouwers, L.A.M. van de Goor, Jostein Rise, H.F.L. Garretsen   +5 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Targeting G9a decreases escalated alcohol drinking in male mice in a model of combined stress and chronic alcohol exposure. [PDF]

Alcohol Clin Exp Res (Hoboken)
Lopez MF, Misztak P, Becker HC, Cowan CW, Anderson EM.   +4 more
europepmc   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Increased alcohol-biased choice behavior in mouse models of high alcohol drinking. [PDF]

Alcohol Clin Exp Res (Hoboken)
Lopez MF, Becker HC.
europepmc   +1 more source

An empirical investigation of the influence of alcohol policy and gender on university students' drinking behaviour [PDF]

, 2016
Bishnu Sharma, Karin Reinhard
openalex  

Commentary on Callaghan et al. (2013): Minimum legal drinking age laws protect high school students from both crashes and alcohol abuse

, 2013
Robert B. Voas
openalex   +1 more source