Results 151 to 160 of about 940,087 (264)
ABSTRACT Diclofenac (DF), a nonsteroidal and anti‐inflammatory drug, has limited use due to its adverse effects on the liver. On the other hand, morin, a bioflavonoid, has biological and pharmacological properties. This study aims to investigate whether morin may protect against diclofenac‐induced liver toxicity.
Nurhan Akaras+5 more
wiley +1 more source
Mitochondria‐Associated Endoplasmic Reticulum Membranes in Human Health and Diseases
MAM dysfunction is considered as an initiator or contributor in the progression of various diseases such as nervous system diseases, circulatory system diseases, digestive system diseases, locomotor system diseases, reproductive system diseases, endocrine system diseases, urinary system diseases, respiratory system diseases and cancer.
Yong Liu+10 more
wiley +1 more source
Oxidative Stress: Signaling Pathways, Biological Functions, and Disease
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu+4 more
wiley +1 more source
The rice pollen‐specific receptor‐like kinases OsPRK1, OsPRK2, and OsPRK3 play a crucial role in reactive oxygen species (ROS)‐mediated pollen hydration and germination. Triple mutants display male sterility due to decreased ROS levels and impaired pollen hydration, and their germination phenotype can be partially restored by exogenous application of ...
Eui‐Jung Kim+9 more
wiley +1 more source
Purification and Characterization of an Alcohol: N,N‐dimethyl‐4‐nitrosoaniline Oxidoreductase from the Methanogen Methanosarcina Barkeri DSM 804 Strain Fusaro [PDF]
Thomas Daußmann+2 more
openalex +1 more source
The gut‐microbiota‐brain axis: Focus on gut steroids
Abstract There are over 1000 varieties of steroids that have been reported in nature, including the endogenous sex steroid hormones (i.e., progesterone, testosterone, and 17β‐estradiol) and corticosteroids which are mainly synthesized by gonads and adrenals, respectively.
Silvia Diviccaro+4 more
wiley +1 more source
Integrated proteomics revealed anthracnose resistance factors in Stylosanthes, identifying the E3 ligase SgATL31 as a positive regulator through ROS and antioxidant pathway modulation. ABSTRACT Stylosanthes spp. (stylo) is an important leguminous forage cultivated in tropical areas.
Liyun Yang+6 more
wiley +1 more source
Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley +1 more source
Christina S Saghaug,1,2 Christian Klotz,3 Juha P Kallio,4 Hans-Richard Brattbakk,1,5 Tomasz Stokowy,1,5 Toni Aebischer,3 Inari Kursula,4,6 Nina Langeland,1–2,7 Kurt Hanevik1,21Department of Clinical Science, University of Bergen, Bergen, Hordaland,
Saghaug CS+8 more
doaj