Results 21 to 30 of about 38,854 (208)

Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202 [PDF]

, 2018
CYP17A1 is a key steroidogenic enzyme known to conduct several distinct chemical transformations on multiple substrates. In its hydroxylase activity, this enzyme adds a hydroxyl group at the 17α position of both pregnenolone and progesterone at ...
Bangcharoenpaurpong O., James R. Kincaid, Mak P. J., Michael C. Gregory, Nakajin S., Piotr J. Mak, Shen A. L., Stephen G. Sligar, Yogan Khatri   +8 more
core   +2 more sources

Molecular basis and biological relevance of bacterial and plant pinoresinol/lariciresinol reductase specificities. [PDF]

Protein Sci
Abstract A bacterial pinoresinol/lariciresinol reductase (PLR) homolog named NrPinZ was obtained from a Novosphingobium rhizosphaerae sp. LY bacterial strain, with NrPinZ being part of its 5‐step biochemical system catabolizing pinoresinol into coniferyl aldehyde and vanillin.
Smith CA, Bedgar DL, Costa MA, Moinuddin SGA, Allemann MN, Michener JK, Davin LB, Lewis NG.   +7 more
europepmc   +2 more sources

Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]

, 2020
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian, Clarke, Clare L., Gandy, Stephen, George, Jacob, Gingles, Christopher, Hutcheon, Anita, Nicholas, Richard S., Priba, Lukasz, Struthers, Allan D., Sumukadas, Deepa, Witham, Miles D.   +10 more
core   +2 more sources

Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids [PDF]

, 2008
Very-long-chain fatty acids (VLCFAs) have long been known to be degraded exclusively in peroxisomes via beta-oxidation. A defect in peroxisomal beta-oxidation results in elevated levels of VLCFAs and is associated with the most frequent inherited ...
Dacremont, Georges, Kemp, Stephan, Ofman, Rob, Sanders, Robert-Jan, Wanders, Ronald J. A.   +4 more
core   +2 more sources

Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene [PDF]

, 2001
The gene for the single subunit, rotenone-insensitive, and flavone-sensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae (NDI1) can completely restore the NADH dehydrogenase activity in mutant human cells that lack the essential ...
Attardi, Giuseppe, Bai, Yidong, Chan, Elisa, Chomyn, Anne, Hájek, Petr, Matsuno-Yagi, Akemi, Seo, Byoung Boo, Yagi, Takao   +7 more
core   +1 more source

The Spermatophore in Glossina morsitans morsitans: Insights into Male Contributions to Reproduction. [PDF]

, 2016
Male Seminal Fluid Proteins (SFPs) transferred during copulation modulate female reproductive physiology and behavior, impacting sperm storage/use, ovulation, oviposition, and remating receptivity.
Abd-Alla, Adly MM, Aksoy, Emre, Aksoy, Serap, Attardo, Geoffrey M, Benoit, Joshua B, Malacrida, Anna R, Michalkova, Veronika, Scolari, Francesca, Takac, Peter   +8 more
core   +2 more sources

The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen [PDF]

, 2014
BACKGROUND: The facultatively anaerobic betaproteobacterium Castellaniella defragrans 65Phen utilizes acyclic, monocyclic and bicyclic monoterpenes as sole carbon source under oxic as well as anoxic conditions.
Becher, D., Disch, E., Harder, J., Huettel, B., Markert, S., Petasch, J., Reinhardt, R., Schweder, T.   +7 more
core   +2 more sources

Tucumanin, a β-hydroxy-γ-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I [PDF]

, 2004
A new β-hydroxy-γ-methyl-γ-lactone bistetrahydrofuranic acetogenin, tucumanin, with the infrequent symmetrical threo/trans/threo/trans/ threo relative configuration at the tetrahydrofuran rings was isolated from Annona cherimolia (Annonaceae) seeds.
Alvarez, Olga, Bardon, Alicia del Valle, Barrachina, Isabel, Bermejo, Almudena, Chahboune, Nadia, El Aouad, Noureddine, Granell, Susana, Neske, Adriana, Zafra Polo, M. Carmen   +8 more
core   +1 more source

Mitochondrial proteomics: analysis of a whole mitochondrial extract with two-dimensional electrophoresis [PDF]

, 2008
Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from cultured mammalian cells, then on the separation of the mitochondrial ...
A. Gorg, C. Tastet, D. Mokranjac, F. Gharahdaghi, F. Granier, H. Zischka, J. C. Sanchez, M. Chevallet, M. Eschenbruch, P. Lescuyer, S. Iwata, S. Luche, S. Luche, S. Richert, T. Rabilloud, T. Tsukihara, V. Santoni   +16 more
core   +6 more sources

Coronatine-insensitive 1 (COI1) mediates transcriptional responses of Arabidopsis thaliana to external potassium supply [PDF]

, 2010
The ability to adjust growth and development to the availability of mineral nutrients in the soil is an essential life skill of plants but the underlying signaling pathways are poorly understood.
Abe, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Armengaud, Armengaud, Ashley, Balbi, Bednarek, Bolstad, Breitling, Breitling, Cao, Chung, Creelman, Devoto, Devoto, Dobermann, Epstein, Evans, Geisler, He, Hull, Jung, Kafkafi, Kim, Laegreid, Li, Maathuis, Maathuis, Marschner, Mikkelsen, Munemasa, Nakano, Okushima, Oria-Hernandez, Otterhag, Pandey, Penninckx, Perez-Amador, Reinbothe, Reymond, Ross, Schachtman, Shin, Shin, Sparla, Staswick, Staswick, Staswick, Sun, Syers, Thines, Tschoep, Vernoud, Véry, Walker, Westphal, Xie, Xu, Yamaguchi-Shinozaki, Yan, Zimmermann   +66 more
core   +6 more sources