Results 61 to 70 of about 940,087 (264)

Mitochondrial proteomics: analysis of a whole mitochondrial extract with two-dimensional electrophoresis [PDF]

, 2008
Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from cultured mammalian cells, then on the separation of the mitochondrial ...
A. Gorg, C. Tastet, D. Mokranjac, F. Gharahdaghi, F. Granier, H. Zischka, J. C. Sanchez, M. Chevallet, M. Eschenbruch, P. Lescuyer, S. Iwata, S. Luche, S. Luche, S. Richert, T. Rabilloud, T. Tsukihara, V. Santoni   +16 more
core   +5 more sources

The Plant Short-Chain Dehydrogenase (SDR) superfamily:genome-wide inventory and diversification patterns [PDF]

, 2012
Background Short-chain dehydrogenases/reductases (SDRs) form one of the largest and oldest NAD(P)(H) dependent oxidoreductase families. Despite a conserved 'Rossmann-fold' structure, members of the SDR superfamily exhibit low sequence similarities, which
Kallberg, Yvonne, Moummou, Hanane, Persson, Bengt, Tonfack, Libert Brice, Van der Rest, Benoît   +4 more
core   +4 more sources

Ethanol production by the hyperthermophilic archaeon Pyrococcus furiosus by expression of bacterial bifunctional alcohol dehydrogenases

Microbial Biotechnology, 2017
Summary Ethanol is an important target for the renewable production of liquid transportation fuels. It can be produced biologically from pyruvate, via pyruvate decarboxylase, or from acetyl‐CoA, by alcohol dehydrogenase E (AdhE).
Matthew W. Keller, Gina L. Lipscomb, Diep M. Nguyen, Alexander T. Crowley, Gerrit J. Schut, Israel Scott, Robert M. Kelly, Michael W. W. Adams   +7 more
doaj   +1 more source

Tucumanin, a β-hydroxy-γ-lactone bistetrahydrofuranic acetogenin from Annona cherimolia, is a potent inhibitor of mitochondrial complex I [PDF]

, 2004
A new β-hydroxy-γ-methyl-γ-lactone bistetrahydrofuranic acetogenin, tucumanin, with the infrequent symmetrical threo/trans/threo/trans/ threo relative configuration at the tetrahydrofuran rings was isolated from Annona cherimolia (Annonaceae) seeds.
Alvarez, Olga, Bardon, Alicia del Valle, Barrachina, Isabel, Bermejo, Almudena, Chahboune, Nadia, El Aouad, Noureddine, Granell, Susana, Neske, Adriana, Zafra Polo, M. Carmen   +8 more
core   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]

, 2004
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
core  

Alcohol drinking and mammary cancer: Pathogenesis and potential dietary preventive alternatives [PDF]

, 2014
Alcohol consumption is associated with an increased risk of breast cancer, increasing linearly even with a moderate consumption and irrespectively of the type of alcoholic beverage.
Castro, Gerardo Daniel, Castro, Jose Alberto   +1 more
core   +1 more source

Genome-Wide SNP Discovery and Mapping QTLs for Seed Iron and Zinc Concentrations in Chickpea (Cicer arietinum L.)

Frontiers in Nutrition, 2020
Biofortification through plant breeding is a cost-effective and sustainable approach towards addressing micronutrient malnutrition prevailing across the globe.
Syed Sab, Syed Sab, Ramappa Lokesha, D. M. Mannur, Somasekhar, Kisan Jadhav, Bingi Pujari Mallikarjuna, Laxuman C, Sharanbasappa Yeri, Vinod Valluri, Prasad Bajaj, Annapurna Chitikineni, AnilKumar Vemula, Abhishek Rathore, Rajeev Kumar Varshney, I. Shankergoud, Mahendar Thudi   +16 more
doaj   +1 more source

Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3

Pharmaceuticals, 2021
PR-104 is a phosphate ester pre-prodrug that is converted in vivo to its cognate alcohol, PR-104A, a latent alkylator which forms potent cytotoxins upon bioreduction.
Maria R. Abbattista, Amir Ashoorzadeh, Christopher P. Guise, Alexandra M. Mowday, Rituparna Mittra, Shevan Silva, Kevin O. Hicks, Matthew R. Bull, Victoria Jackson-Patel, Xiaojing Lin, Gareth A. Prosser, Neil K. Lambie, Gabi U. Dachs, David F. Ackerley, Jeff B. Smaill, Adam V. Patterson   +15 more
doaj   +1 more source

Synthesis of pyruvate: ferredoxin oxidoreductase and alcohol dehydrogenase E enzymes during Giardia intestinalis excystation.

Biomedica : revista del Instituto Nacional de Salud, 2010
INTRODUCTION Giardia intestinalis is a unicellular parasite of worldwide distribution. It causes an intestinal illness known as giardiasis, and it is probably the earliest diverging eukaryotic microorganism.
C. A. Niño, M. Wasserman
semanticscholar   +1 more source