Results 151 to 160 of about 943,763 (288)
Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Nurshad Ali
wiley +1 more source
Recent Advances in the Bioactive Compounds of Prunes (Prunus domestica L.) and Their Health Benefits
Food Frontiers, Volume 7, Issue 1, January 2026.Prunes (Prunus domestica L.) are a functional food rich in diverse bioactive compounds, including polyphenols (such as chlorogenic acid and anthocyanins), polysaccharides, and sorbitol.This review comprehensively synthesizes current research on the nutritional composition and biological activities of prunes, highlighting their multifaceted health ...
Luyang Han +10 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 1, January 2026.Biological activities, health benefits and structures of equol and its derivatives. ABSTRACT Equol is a metabolite transformed from daidzein by intestinal microorganisms and has received extensive attention due to its various pharmacological activities and therapeutic potential.
Jiao‐Jiao Zhuo +2 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 1, January 2026.The Morchella mycelium polysaccharide (MP), a homogeneous α‐glucan (96.555% glucose, 5.7 kDa), protects against alcohol‐induced liver injury in mice. It reduces serum ALT/AST, improves lipid metabolism, and enhances antioxidants and inhibiting lipid peroxidation. Mechanistically, the MP suppresses Nlrp3 inflammasome‐mediated inflammation/pyroptosis and
Xinyu Hu +10 more
wiley +1 more source
Small, Volume 22, Issue 5, 22 January 2026.Nucleic acid‐ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified products are paramount, requiring reliable synthesis and purification methods.
Nico Alleva +4 more
wiley +1 more source
Exploring and Validating the Molecular Mechanisms Linking Fatty Acid Metabolism and Sarcopenia
IET Systems Biology, Volume 20, Issue 1, January/December 2026.This study provides reference for fatty acid metabolism related potential candidate genes for sarcopenia and initially creates an effective machine learning models for further investigating the direction of the mechanism level. ABSTRACT Sarcopenia is an ageing‐related disease characterised primarily by skeletal muscle functional decline.
Ruopeng Yang, Shan Gu, Yang Li, Ping Xia
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 1, January 2026.Genome‐wide association analysis on 49 Sinorhizobium meliloti strains (21 de novo sequenced) reveals extensive phenotypic heterogeneity in salt tolerance, closely associated with quorum sensing, cell surface stability and adaptation. Salt‐tolerant strains exhibit a wider metabolic capacity, especially in carbon sources exploitation, underscoring their ...
Agnese Bellabarba +12 more
wiley +1 more source
Iron-Containing Alcohol Dehydrogenase from Hyperthermophiles. [PDF]
BioTech (Basel)Tse C, Ma K.
europepmc +1 more source
Supersulfide biology and translational medicine for disease control
British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source