Results 61 to 70 of about 9,259 (270)

Bail-out alcohol septal ablation in the management of obstructive hypertrophic cardiomyopathy and refractory electrical storm. Case resolution

open access: yesREC: Interventional Cardiology (English Ed.), 2020
CASE RESOLUTION The outcome was successful with a final 19-mmHg intraventricular gradient and after the extrasystole of 25 mmHg (figure 1). No more new events of ventricular tachycardia (VT) were reported, disease progression was good, and the patient ...
Piero Custodio-Sánchez   +5 more
doaj   +1 more source

Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy

open access: yesJournal of Interventional Cardiology, 2005
HOCM is a rare disorder of myocardium that may result in asymmetrical left ventricular septal hypertrophy and dynamic outflow obstruction. This may result in hemodynamic sequel that leads to deterioration of functional class in the majority of patients. Alcohol septal ablation may provide symptomatic relief in the majority of patients who fail medical
Amr E. Abbas   +4 more
openaire   +5 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Hypertrophic obstructive cardiomyopathy: alcohol septal ablation [PDF]

open access: yes, 2017
Alcohol septal ablation (ASA) was introduced in 1994 as an alternative to septal myectomy for patients with hypertrophic obstructive cardiomyopathy and symptoms refractory to medical therapy.
Fifer, Michael A., Sigwart, Ulrich
core  

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang   +9 more
wiley   +1 more source

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]

open access: yes, 2018
Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui   +9 more
core   +2 more sources

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

open access: yesAdvanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu   +16 more
wiley   +1 more source

Hypertrophic Cardiomyopathy - Past, Present and Future [PDF]

open access: yes, 2017
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy with a prevalence of 1 in 500 in the general population. Since the first pathological case series at post mortem in 1957, we have come a long way in its understanding, diagnosis ...
Brock   +5 more
core   +2 more sources

From 100 to 0

open access: yesJACC: Case Reports, 2020
Septal reduction techniques can reduce morbidity and mortality in patients with hypertrophic cardiomyopathy. In a patient with hypertrophic cardiomyopathy who was a poor candidate for surgical myectomy and alcohol septal ablation, endocardial ...
Graham Peigh, MD   +4 more
doaj  

Non-pharmaceutical Interventions for Hypertrophic Cardiomyopathy: A Mini Review

open access: yesFrontiers in Cardiovascular Medicine, 2021
Hypertrophic cardiomyopathy is an inherited cardiovascular disease, and 70% of patients have left ventricular outflow tract obstruction. Ventricular septal myectomy has been the gold standard treatment for most patients with refractory symptoms.
Miaomiao He   +5 more
doaj   +1 more source

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