Results 71 to 80 of about 8,294 (235)

The FKBP5 Gene Affects Alcohol Drinking in Knockout Mice and Is Implicated in Alcohol Drinking in Humans [PDF]

, 2016
FKBP5 encodes FK506-binding protein 5, a glucocorticoid receptor (GR)-binding protein implicated in various psychiatric disorders and alcohol withdrawal severity.
Boehm II, Stephen L., Chester, Julia A., Eng, Mimy Y., Kirchhoff, Aaron M., Liang, Tiebing, Luczak, Susan E., Qiu, Bin, Shou, Weinian, Steward, Robert B., Wall, Tamara L., Xu, Yuxue, Yong, Weidong   +11 more
core   +4 more sources

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Is subcutaneous fat tissue embolization effective and safe as a septal reduction technique in a patient with hypertrophic obstructive cardiomyopathy?

Türk Kardiyoloji Derneği Arşivi, 2018
Hypertrophic obstructive cardiomyopathy is an inheritable cardiac disease that typically manifests with an increased left ventricular outflow tract gradient.
Elnur Alizade, Sabahattin Gündüz, Ahmet Güner, Khagani Isgandarov, Selçuk Pala   +4 more
doaj   +1 more source

Improvement in diastolic suction in patients with hypertrophic obstructive cardiomyopathy after septal ablation [PDF]

, 2002
Background: The ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS) version 1.0 (v1.0) was published in May 2015 and was the first version of a validated and reproducible tool to assess the magnitude of clinical benefit from new cancer therapies.
Garcia, Mario J., Greenberg, Neil L., Lever, Harry M., Rovner, Aleksandr, Shiota, Takahiro, Sitges, Marta, Smedira, Nicholas, Smith, Rebecca, Thomas, James D., Tuzcu, Murat E., Vlassak, Irmien   +10 more
core   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

Alcohol Septal Ablation of Hyperthropic Obstructive Cardiomyopathy Patient with Respiratory Failure

Majalah Kardiologi Indonesia, 2013
Hypertrophic Obstructive Cardiomyopathy (HOCM) prevalence is about 1 among 500 population. It is caused by genetic malformation. Dyspnoe, angina pectoris and syncope are clinical manisfestation.
Jusuf Endang, H Haryadi, Siska Suridanda, Andika S, Roy Christian, I Irmalita, Sunu Budi Raharjo, Yoga Yuniadi   +7 more
doaj   +1 more source

A Comprehensive Review of the Genetic Etiology and Management of Orofacial Clefts

Pediatric Discovery, EarlyView.
ABSTRACT Cleft lip (CL) and cleft palate (CP), collectively referred to as orofacial clefts (OFCs), are among the most common birth defects and can have significant effects on speech, nutrition, and physical and psychosocial development. Manifestation, classification, and treatment plans of OFCs are diverse and not standardized.
Emily Kim, Rebeka Dejenie, Caroline Kim, Russell Reid   +3 more
wiley   +1 more source

Successful Percutaneous Septal Alcohol Ablation After Surgical Myectomy

Biomolecules & Biomedicine, 2010
Hypertrophic obstructive cardiomyopathy (HOCM) is a primary, usually familial and genetically fixed myocardial hypertrophy, with dynamic left ventricular outflow tract obstruction.
Mehmed Kulić, Muhamed Spužić, Elnur Tahirović, Šejla Šehović, Vedad Mujačić, Darko Zorman, Vladimir Velebit   +6 more
doaj   +1 more source

Two Hearts at Risk

JACC: Case Reports, 2020
Hypertrophic obstructive cardiomyopathy (HOCM) increases the risk for mother and fetus during pregnancy. Alcohol septal ablation (ASA) is an established procedure in nonpregnant patients with HOCM. In this report, we present a case of a 29-year-old woman
Weng-Tein Gi, MD, MSc, Ali Amr, MD, Farbod Sedaghat-Hamedani, MD, Elham Kayvanpour, MD, Isabell Mohr, BSc, Manuela Meder, MD, Omid Shirvani Samani, MD, Herbert Fluhr, MD, Hugo A. Katus, MD, Benjamin Meder, MD   +9 more
doaj   +1 more source