Results 71 to 80 of about 9,259 (270)

Alcohol septal ablation for obstructive hypertrophic cardiomyopathy [PDF]

Heart, 2006
Hypertrophic cardiomyopathy (HCM) is a genetic condition characterised by the presence of otherwise unexplained left ventricular hypertrophy. The clinical spectrum of the disease is remarkably heterogeneous, ranging from individuals with normal life expectancy and minimal symptoms to those with lives severely restricted by breathlessness and chest pain
openaire   +3 more sources

In Situ Assembly of Fluorogenic RNA for Screening Natural Anti‐Liver Fibrosis Products via Dynamic Visualization of COL1A1 mRNA

Advanced Science, EarlyView.
This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai, Li‐Zeng Zhu, Changfa Shao, Zheng Yin, Qun Liu, Yu Gu, Bin Liu   +6 more
wiley   +1 more source

Sepsis-induced suicidal left ventricular in a patient with hypertrophic cardiomyopathy/hypertrophic obstructive cardiomyopathy

Apollo Medicine, 2022
Hypertrophic cardiomyopathy is the most common heritable cardiomyopathy, manifesting as left ventricular hypertrophy. In this case, a 48-year-male patient presented with complaints of shortness of breath, uneasiness for 15 days, right lower limb pain ...
K Roshan Rao, Sarita Rao, Ankur Gupta
doaj   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

Advanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai, Xuan Lu, Xu Yan, Han Su, Yuejun Lin, Zhaowei Jiang, Zhixian Zong, Haixing Wang, Leo Yik Chun Yan, Xiaoting Zhang, Ming Wang, Zhengmeng Yang, Jiakang Jin, Yaofeng Wang, Wayne Yuk‐Wai Lee, Xiaohua Jiang, Ho Ko, Lu Feng, Micky D. Tortorella, Sien Lin, Gang Li   +20 more
wiley   +1 more source

Ablación septal con alcohol guiada con ecocardiograma para el manejo de la cardiopatía hipertrófica obstructiva

Revista Colombiana de Cardiología, 2019
Resumen: Objetivo: Reportar el primer caso de ablación septal con alcohol guiada por ecocardiografía realizada en la Costa Atlántica. Material y métodos: Paciente femenina de 74 años de edad con cuadro clínico de disnea, dolor anginoso y síncope ...
Celin Malkun Paz, Pedro Graziano Sánchez, Manuel Rojano Ruiz   +2 more
doaj  

Surgical Myectomy after Failed Ablation for Hypertrophic Obstructive Cardiomyopathy

The Thoracic & Cardiovascular Surgeon Reports, 2016
Background Hypertrophic cardiomyopathy is a genetic disease of the myocardial sarcolemma characterized by left ventricular hypertrophy. When obstruction to the left ventricular outflow tract is present and symptoms are refractory to medication, surgical ...
Ioannis Bougioukas, Uta Hoppe, Bernhard Danner, Friedrich A. Schoendube   +3 more
doaj   +1 more source

Bacterial Minicell‐Based Biohybrid Sub‐micron Swimmers for Targeted Cargo Delivery

Advanced Science, EarlyView.
Bacterial minicells, vesicles derived from engineered E. coli, offer promising sub‐micron scale biohybrid swimmers for targeted cargo delivery. Purified with over 99% efficiency while retaining motility, they are functionalized with MNPs for controlled movement.
Saadet Fatma Baltaci, Mukrime Birgul Akolpoglu, Irina Kalita, Victor Sourjik, Metin Sitti   +4 more
wiley   +1 more source

Septal myectomy for hypertrophic obstructive cardiomyopathy: coil, boil and the role of rescue surgery [PDF]

, 2017
Interventional treatment of hypertrophic obstructive cardiomyopathy has considerably developed and primary surgical approach is nowadays considered for a minority of patients with insufficient relief of obstruction following catheter intervention.
Carrel, Thierry, Schmidli, Jürg
core  

Exercise Echocardiography in Asymptomatic HCM Exercise Capacity, and Not LV Outflow Tract Gradient Predicts Long-Term Outcomes [PDF]

, 2014
ObjectivesThis study sought to assess long-term outcomes in asymptomatic or minimally symptomatic patients with hypertrophic cardiomyopathy (HCM) who underwent exercise echocardiography, without invasive therapies for relief of left ventricular outflow ...
Bhonsale, Aditya, Desai, Milind Y., Lever, Harry M., Lytle, Bruce W., Naji, Peyman, Patel, Parag, Smedira, Nicholas G., Thamilarasan, Maran   +7 more
core   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source