Results 41 to 50 of about 2,622,964 (299)

Protein Kinases as Mediators for miRNA Modulation of Neuropathic Pain

Cells
Neuropathic pain is a chronic condition resulting from injury or dysfunction in the somatosensory nervous system, which leads to persistent pain and a significant impairment of quality of life.
Leah Chang, Zala Čok, Lei Yu
doaj   +1 more source

Reliability of the GAIN-SS, CRAFTT and PESQ screening instruments for substance use among South African adolescents

South African Journal of Psychiatry, 2016
Introduction: Screening for adolescent substance use can assist with the early identification of substance-related problems and guide the provision of appropriate services. As such, psychometrically sound screening tools are needed. The aim of this study
Tara Carney, Bronwyn Myers, Johann Louw
doaj   +1 more source

Alcohol use and alcohol-use disorders among older adults in India: a literature review.

, 2013
OBJECTIVES: With changing attitudes to alcohol and an increasing life span in India, the prevalence of alcohol use and misuse in successive cohorts of older people is likely to increase.
Crome, Ilana B, Murthy, Pratima, Nadkarni, Abhijit, Rao, Rahul   +3 more
core   +1 more source

Short screening tools for risky drinking in Aboriginal and Torres Strait Islander Australians: modified AUDIT-C and a new approach

Addiction Science & Clinical Practice, 2019
Background Alcohol consumption among Indigenous Australians can involve a stop-start pattern of drinking, with consumption well above recommended guidelines on each occasion.
K. S. Kylie Lee, James H. Conigrave, Scott Wilson, Jimmy Perry, Sarah Callinan, Robin Room, Tanya N. Chikritzhs, Tim Slade, Noel Hayman, Geoffrey Leggat, Katherine M. Conigrave   +10 more
doaj   +1 more source

The role of alcohol response phenotypes in the risk for alcohol use disorder [PDF]

, 2019
Heavy alcohol use is pervasive and one of our most significant global health burdens. Early theories posited that certain alcohol response phenotypes, notably low sensitivity to alcohol (‘low-level response’) imparts risk for alcohol use disorder (AUD ...
Cao, Dingcai, deWit, Harriet, Hasin, Deborah S., King, Andrea C., O'Connor, Sean J.   +4 more
core   +1 more source

Participant experiences with a text message and contingency management intervention for alcohol use during pregnancy and lactation in Cape Town, South Africa

Addiction Science & Clinical Practice
Background The Western Cape region of South Africa has one of the highest global rates of Fetal Alcohol Spectrum Disorder (FASD), underscoring the urgent need for effective interventions. This qualitative study, designed as a process evaluation, explores
Lesley-Ann Erasmus-Claassen, Noluthando Mpisane, Petal Petersen Williams, Felicia A. Browne, Bronwyn Myers, Wendee M. Wechsberg, Charles D. H. Parry, Shantae N. Taylor, Yukiko Washio   +8 more
doaj   +1 more source

Evidence Based Treatment for Excessive Alcohol Consumption and Concurrent Hypertension [PDF]

, 2020
Purpose. Excessive alcohol consumption is a preventable risk factor for hypertension, heart disease, and stroke. Though alcohol-related deaths number 88,000 annually in the U.S., alcohol use has the lowest treatment rate of behavioral health disorders at
Ward, Kimberly Ann
core   +1 more source

Do drinking motives mediate the relationship between neighborhood characteristics and alcohol use among adolescents? [PDF]

, 2019
Funding: Funding for the Scottish Health Behaviour in School-aged Children was provided by NHS Scotland. This work was also supported by the 600th Anniversary Ph.D.
Browne, Candace Currie, Cooper, Flowerdew, Geiser, Gelman, Gina Martin, Joanna Inchley, Katz, Khana, Leckie, Sudhinaraset   +11 more
core   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Community-based drug checking at syringe service programs in New York City observe an increasing prevalence of xylazine from 2021 through 2024

Harm Reduction Journal
Background Xylazine has emerged as a major component of the unregulated opioid supply in several jurisdictions across the United States. However, the extent of xylazine in local drug supplies is unknown.
Leonardo A. Dominguez Gomez, Yarelix Estrada, Jeffery Sauer, Izza Zaidi, Andrew J. Trinidad, Hannah Helmy, Alex Harocopos   +6 more
doaj   +1 more source