Results 91 to 100 of about 2,165,233 (395)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Mental health in UK Biobank - development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis [PDF]

, 2020
Background UK Biobank is a well-characterised cohort of over 500 000 participants including genetics, environmental data and imaging. An online mental health questionnaire was designed for UK Biobank participants to expand its potential.
Adams, M., Allen, N., Breen, G., Coleman, J. R. I., Cullen, B., Davis, K. A. S., Dickens, C., Fox, E., Graham, N., Holliday, J., Hotopf, M., Howard, L. M., John, A., Lee, W., McCabe, R., McIntosh, A., Pearsall, R., Smith, D. J., Sudlow, C., Ward, J., Zammit, S.   +20 more
core   +8 more sources

Borderline personality disorder and substance use disorders: an updated review

Borderline Personality Disorder and Emotion Dysregulation, 2018
For decades, clinicians and researchers have recognized that borderline personality disorder (BPD) and substance use disorders (SUDs) are often diagnosed within the same person (e.g., (Gunderson JG.
Timothy J. Trull, Lindsey K. Freeman, Tayler J. Vebares, Alexandria M. Choate, Ashley C. Helle, Andrea M. Wycoff   +5 more
doaj   +1 more source

Sex and Gender Effects in Recovery From Alcohol Use Disorder

Alcohol research : current reviews, 2020
The current article provides a brief summary of biopsychosocial gender differences in alcohol use disorder (AUD), then reviews existing literature on gender differences in treatment access, retention, outcomes, and longer-term recovery.
C. G. Holzhauer, Michael A. Cucciare, E. Epstein   +2 more
semanticscholar   +1 more source

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang, Haiting Li, Xiaoping Du, Qiong Wang, Yating Zhang, Huifang Wang   +5 more
wiley   +1 more source

Intravenous ketamine for severe alcohol use disorder at Moi Teaching & Referral Hospital, Kenya: a case report

Substance Abuse Treatment, Prevention, and Policy, 2023
Background Alcohol use disorder is prevalent globally and in Kenya, and is associated with significant health and socio-economic consequences. Despite this, available pharmacological treatment options are limited.
Florence Jaguga, Philip Kirwa, Benson Gakinya, Imran Manji, Thomas Andale, Daniel Kinyanjui, Edith Kamaru Kwobah, Felicita Mwangi, Kituyi Werunga, Josephat Kerema, Charles Kwobah, Eunice Temet, Julia Songok, Wilson K. Aruasa   +13 more
doaj   +1 more source

Alcohol Use Disorders in Pregnancy [PDF]

Harvard Review of Psychiatry, 2015
Alcohol use disorders (AUDs) are less prevalent in pregnant women than in nonpregnant women, but these disorders can create a host of clinical challenges when encountered. Unfortunately, little evidence is available to guide clinical decision making in this population.
Roger D. Weiss, Olivera Bogunovic, Jeffrey DeVido   +2 more
openaire   +3 more sources

Advances in the science and treatment of alcohol use disorder

Science Advances, 2019
Pharmacological and behavioral treatments exist for alcohol use disorder, but more are needed, and several are under development. Alcohol is a major contributor to global disease and a leading cause of preventable death, causing approximately 88,000 ...
K. Witkiewitz, R. Litten, L. Leggio, L. Leggio, L. Leggio   +4 more
semanticscholar   +1 more source

Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad, Lili Zhou, Brian Manolovitz, Negar Asdaghi, Hannah Gardener, Hao Ying, Carolina M. Gutierrez, Angus Jameson, David Rose, Mohan Kottapally, Amedeo Merenda, Kristine O'Phelan, Sebastian Koch, Jose G. Romano, Tatjana Rundek, Ayham Alkhachroum   +15 more
wiley   +1 more source

Substance Use Disorder Is Associated With Alcohol-Associated Liver Disease in Patients With Alcohol Use Disorder

Gastro Hep Advances, 2022
Background and Aims: Substance use disorder (SUD) commonly associates with alcohol use disorder (AUD), and certain substances have independently been shown to drive liver injury. In this work, we sought to determine if coexisting SUD in patients with AUD
Augustin G.L. Vannier, Vladislav Fomin, Raymond T. Chung, Suraj J. Patel, Esperance Schaefer, Russell P. Goodman, Jay Luther   +6 more
doaj