Results 141 to 150 of about 586,881 (303)

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

Advanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou, Johanna Simon, Moritz Beck‐Broichsitter, Gary Davidson, Pavel A. Levkin   +4 more
wiley   +1 more source

Thin Film Stoichiometry and Defects Management for Low Threshold and Air Stable Near‐Infrared Perovskite Laser

Advanced Materials, EarlyView.
As defect density in 3D perovskites is controlled by adjusting excess formamidinium iodide concentration, shallow defects acts as a carrier sink for amplified spontaneous emission (ASE). A comprehensive charge carrier dynamic model is presented to understand the critical factor of the reduction of ASE threshold.
Chun‐Sheng Jack Wu, Andrea Olivati, Giulia Folpini, Heyong Wang, Annamaria Petrozza   +4 more
wiley   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Evaluation of a new trauma-related drinking to cope measure: Latent structure and heritability [PDF]

, 2019
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) commonly co-occur, share latent genetic risk, and are associated with many negative public health outcomes.
Aggen, Steven H., Amstadter, Ananda B, PhD, Dick, Danielle, Hawn, Sage E.   +3 more
core   +1 more source

Materials, Structure, and Interface of Stretchable Interconnects for Wearable Bioelectronics

Advanced Materials, EarlyView.
Stretchable interconnects are one of the fundamental components in achieving robust wearable devices, but their importance is often overlooked. This review highlights their importance and provides insightful information on various materials, configurations, and manufacturing approaches being studied for interconnects.
Yue Li, Asmita Veronica, Jiahao Ma, Hnin Yin Yin Nyein   +3 more
wiley   +1 more source

Alcohol use disorder research in India: An update

Indian Journal of Psychiatry
Background: Despite alcohol use being a risk factor for numerous health-related conditions and alcohol use disorder (AUD) recognized as a disease, there was limited research in India until 2010. This narrative review aims to evaluate AUD-related research
Venkata Lakshmi Narasimha, Diptadhi Mukherjee, Sidharth Arya, Arpit Parmar   +3 more
doaj   +1 more source

Pushing Radiative Cooling Technology to Real Applications

Advanced Materials, EarlyView.
Radiative cooling controls surface optical properties for solar and thermal radiation, offering solutions for global warming and energy savings. Despite significant advances, key challenges remain: optimizing optical efficiency, maintaining aesthetics, preventing overcooling, enhancing durability, and enabling scalable production.
Chongjia Lin, Keqiao Li, Meng Li, Benjamin Dopphoopha, Jiongzhi Zheng, Jiazheng Wang, Shanshan Du, Yang Li, Baoling Huang   +8 more
wiley   +1 more source

The Efficacy of Gabapentin in the Treatment of Alcohol Use Disorder

Quality in Sport
Introduction: Alcohol Use Disorder (AUD) is a significant medical condition characterized by an inability to control alcohol use despite adverse consequences, ranging from occasional excessive drinking to daily dependency. Treatment for AUD involves
Radosław Zaucha, Magdalena Gajkiewicz, Małgorzata Zając, Julia Silldorff, Tomasz Fura, Marcin Dudek, Zuzanna Felińska, Oliwia Iszczuk, Stanisław Anczyk, Magdalena Jaskółka   +9 more
doaj   +1 more source

Computational Modeling of Reticular Materials: The Past, the Present, and the Future

Advanced Materials, EarlyView.
Reticular materials are advanced materials with applications in emerging technologies. A thorough understanding of material properties at operating conditions is critical to accelerate the deployment at an industrial scale. Herein, the status of computational modeling of reticular materials is reviewed, supplemented with topical examples highlighting ...
Wim Temmerman, Ruben Goeminne, Kuber Singh Rawat, Veronique Van Speybroeck   +3 more
wiley   +1 more source

Strategies for Controlling Emission Anisotropy in Lead Halide Perovskite Emitters for LED Outcoupling Enhancement

Advanced Materials, EarlyView.
The rise of lead halide perovskite semiconductors has enabled high‐performance LEDs with internal quantum efficiencies approaching 100%. In order to further enhance the external quantum efficiencies limited by light outcoupling effects, in this account, the strategies for reducing energy dissipation through the substrate, waveguide, and evanescent ...
Tommaso Marcato, Sudhir Kumar, Chih‐Jen Shih   +2 more
wiley   +1 more source