ZSCAN25 methylation predicts seizures and severe alcohol withdrawal syndrome
Currently, clinicians use their judgement and indices such as the Prediction of Alcohol Withdrawal Syndrome Scale (PAWSS) to determine whether patients are admitted to hospitals for consideration of withdrawal syndrome (AWS).
Allan Andersen +10 more
doaj +4 more sources
Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures. [PDF]
Adenosine is involved in several neurological and behavioral disorders including alcoholism. In cultured cell and animal studies, type 1 equilibrative nucleoside transporter (ENT1, slc29a1), which regulates adenosine levels, is known to regulate ethanol ...
Jeong-Hyun Kim +10 more
doaj +3 more sources
Plasma homocysteine is a predictor of alcohol withdrawal seizures
An adaptive consequence of prolonged ethanol consumption is a compensatory up-regulation of NMDA receptors in certain brain areas. Taking into account that homocysteine and its breakdown products (i.e. homocysteic acid) are putative neurotransmitters and agonists at the NMDA receptor, the aim of this study was to assess the influence of levels of ...
Bleich, Stefan +5 more
openaire +4 more sources
Association of single nucleotide variants of the clock gene (rs1801260) with seizures after alcohol withdrawal [PDF]
Objective: to study the association of single nucleotide variants of the CLOCK gene (rs1801260) and seizures aſter alcohol withdrawal.Materials and methods: 399 patients were analyzed, including 83 women (21%) and 316 men (79%).
R. S. Achuvakov +5 more
doaj +2 more sources
Risk assessment of alcohol withdrawal seizures with a Kohonen feature map
Recently, it has been suggested that alcohol-induced hyperhomocysteinaemia in patients suffering from chronic alcoholism might be a risk factor for alcohol withdrawal seizures. In the present follow-up study 12 patients with chronic alcoholism who suffered from withdrawal seizures had significantly higher levels of homocysteine (Hcy) on admission (71 ...
Kurth, C. +6 more
openaire +4 more sources
Management of Alcohol Withdrawal Syndrome and Alcohol Withdrawal Seizure [PDF]
Alcohol withdrawal syndrome (AWS) is a common condition occurring after intentional or unintentional abrupt cessation of alcohol in an alcohol-dependent individual. AWS represents a major problem in our society and alcohol withdrawal seizure is the major
Kyoung Heo +5 more
openaire +3 more sources
Role of Standardized Plant Extracts in Controlling Alcohol Withdrawal Syndrome—An Experimental Study
Patients with alcohol use disorder experience alcohol withdrawal syndrome due to the sudden cessation of alcohol. This study was designed to evaluate the protective effect of Ashwagandha and Brahmi on alcohol withdrawal in rats. Thirty rats of either sex
Ijasul M. Haque +3 more
doaj +1 more source
Activity of hippocampal adult-born neurons regulates alcohol withdrawal seizures. [PDF]
Alcohol withdrawal (AW) after chronic alcohol exposure produces a series of symptoms, with AW-associated seizures being among the most serious and dangerous. However, the mechanism underlying AW seizures has yet to be established.
Lee D +6 more
europepmc +2 more sources
Self-Injurious Behavior in Alcohol Withdrawal State Complicated by Delirium – A Case Series
Regular and excessive use of alcohol can produce dependence over a period of time. Individuals who stops or reduces the alcohol use suddenly can have withdrawal symptoms ranging from tremors, altered sensorium, Delirium and seizures.
S V Sathish Kumar, N V Roopesh Gopal
doaj +1 more source
Alcoholic withdrawal syndrome and seizures [PDF]
A study of 72 alcoholics, hospitalized for alcohol withdrawal syndrome, was undertaken to determine the incidence of seizures, their relationship with other withdrawal symptoms, the presence of brain atrophy and the relationship of this last with withdrawal intensity severity. Sixty-seven (93%) were male and the mean age was 44.9 +/- 1.3 (mean +/- SEM)
H, Essardas Daryanani +7 more
openaire +3 more sources

