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Challenges in Nursing Care of Children With Substance Withdrawal Syndrome in the PICU [PDF]

SAGE Open Nursing, 2022
Introduction Substance withdrawal is one of the most common advert events in the Pediatric Intensive Care Unit (PICU), as the administration of potent opiates and sedative drugs is frequently performed several times each day. Objectives The present study
Janet Mattsson PhD, Johannes Meijers MSN, Gunilla Björling PhD   +2 more
doaj   +5 more sources

The Impact of Saffron Crocin on Clinical and Psychological Complications of Opioid Substance Withdrawal Syndrome: A Systematic Review of in vivo and Clinical Trial Studies [PDF]

Journal of Advanced Biomedical Sciences
Background & Objectives: Drug addiction constitutes a global issue associated with severe personal, economic, social, and health problems. Saffron, an herbal medicine, has demonstrated potential therapeutic applications for mental and physical symptoms ...
Mitra Tavakolizadeh, Ali Akbari, Akram Bakhtiari Shahri, Sina Sabeti Bilondi, Vida Alikhani   +4 more
doaj   +5 more sources

Overview of withdrawal syndrome mechanisms in different substance abuse addictions: Neuronal circuits and transmitters [PDF]

Journal of Addiction Medicine and Therapeutic Science, 2020
Substance abuse is one of the major concerns of human societies. Many problems exist for controlling drug abuse that profoundly influences treatment. One of the most important and prevalent problems is Withdrawal Syndrome (WS).
Famitafreshi Hamidreza, Karimian Morteza
openaire   +2 more sources

Increased Incidence of Urinary Tract Infections in Newborns With Neonatal Opiate Withdrawal Syndrome Treated With Morphine and Clonidine: A Case Series With Supplemental Descriptive Cohort Data [PDF]

Case Reports in Pediatrics
Neonatal opioid withdrawal syndrome has become a prevalent diagnosis with the rise of maternal substance use during pregnancy. Manifestation of this syndrome is characterized by altered activity of the central nervous system with symptoms including ...
Alexandra A. Richmond, M. Cody Smith, Micah Butcher, Lesley Cottrell, Mark J. Polak   +4 more
doaj   +2 more sources

Effectiveness and Safety of Haloperidol Add-on Methadone in Acute Opium Withdrawal Symptoms of Opioid-dependent Patients: A Double-blind Randomized Placebo-controlled Clinical Trial [PDF]

Addiction and Health, 2021
Background: The aim of this double-blind clinical trial was to evaluate the efficacy and safety of haloperidol on acute opioid withdrawal symptoms. Methods: In this randomized double-blind clinical trial, fifty-two eligible patients were assigned to two ...
Fattaneh Ghaderi-Bafti, Mehran Zarghami, Abdolkarim Ahmadi, Mahmood Moosazadeh, Pezhman Hadinezhad, Narjes Hendouei   +5 more
doaj   +1 more source

Is Clonidine Useful for the Management of Tramadol-induced Withdrawal Syndrome? [PDF]

Asia Pacific Journal of Medical Toxicology, 2022
Dear Editor-in-chiefTramadol is a synthetic opioid with non-opioid effects. It has a low affinity to opioid receptors and inhibits re-uptake of norepinephrine and serotonin in synapses [1- 5].
Mohammad Majidi, Solmaz Nekoueifard, Bita Dadpour   +2 more
doaj   +1 more source

A Retrospective Review Following the Addition of Clonidine to a Neonatal Abstinence Syndrome Treatment Algorithm

Frontiers in Pediatrics, 2021
Objective: To investigate the outcomes associated with the implementation of a neonatal abstinence syndrome (NAS) treatment algorithm utilizing dual therapy with morphine sulfate and clonidine in a level four neonatal intensive care unit (NICU).Study ...
Mohammad Y. Bader, Mohammad Y. Bader, Nahla Zaghloul, Nahla Zaghloul, Ashley Repholz, Nadia Nagy, Nadia Nagy, Mohamed N. Ahmed, Mohamed N. Ahmed, Leslie Thompson, Ranjit I. Kylat, Ranjit I. Kylat   +11 more
doaj   +1 more source

Efficacy of Lofexidine in the Outpatient Management of Tramadol Withdrawal Syndrome

International Journal of Medical Toxicology and Forensic Medicine, 2020
Tramadol is recognized as an opioid with non-opiate properties. It has a low affinity for opioid receptors and prevents reabsorption of norepinephrine and serotonin at synapses. It also increases the level of Gamma Aminobutyric Acid (GABA) in the central
Mohammad Majidi , Solmaz Nekoueifard
doaj   +1 more source

Inhibition of NMDA receptors by agmatine is followed by GABA/glutamate balance in benzodiazepine withdrawal syndrome

Beni-Suef University Journal of Basic and Applied Sciences, 2021
Background Drug withdrawal syndrome occurs due to abrupt cessation of an addictive substance. Dependence to diazepam can be manifested by withdrawal syndrome which may include symptoms such as irritability, psychosis, sleep disturbance, seizures, mood ...
Hira Rafi, Hamna Rafiq, Muhammad Farhan
doaj   +1 more source

Cognitive and Mental Health Predictors of Withdrawal Severity During an Active Attempt to Cut Down Cannabis Use

Frontiers in Psychiatry, 2018
A milestone in cannabis research is the establishment of a clinically relevant cannabis withdrawal syndrome, yet little is known about the underlying mechanisms.
Janna Cousijn, A. C. K. van Duijvenvoorde, A. C. K. van Duijvenvoorde   +2 more
doaj   +1 more source