Results 11 to 20 of about 1,718,878 (260)

Efficacy of Lofexidine in the Outpatient Management of Tramadol Withdrawal Syndrome

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
Tramadol is recognized as an opioid with non-opiate properties. It has a low affinity for opioid receptors and prevents reabsorption of norepinephrine and serotonin at synapses. It also increases the level of Gamma Aminobutyric Acid (GABA) in the central
Mohammad Majidi , Solmaz Nekoueifard
doaj   +1 more source

Inhibition of NMDA receptors by agmatine is followed by GABA/glutamate balance in benzodiazepine withdrawal syndrome

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2021
Background Drug withdrawal syndrome occurs due to abrupt cessation of an addictive substance. Dependence to diazepam can be manifested by withdrawal syndrome which may include symptoms such as irritability, psychosis, sleep disturbance, seizures, mood ...
Hira Rafi, Hamna Rafiq, Muhammad Farhan
doaj   +1 more source

Cognitive and Mental Health Predictors of Withdrawal Severity During an Active Attempt to Cut Down Cannabis Use

open access: yesFrontiers in Psychiatry, 2018
A milestone in cannabis research is the establishment of a clinically relevant cannabis withdrawal syndrome, yet little is known about the underlying mechanisms.
Janna Cousijn   +2 more
doaj   +1 more source

Using Named Entity Recognition to Identify Substances Used in the Self-medication of Opioid Withdrawal: Natural Language Processing Study of Reddit Data

open access: yesJMIR Formative Research, 2022
BackgroundThe cessation of opioid use can cause withdrawal symptoms. People often continue opioid misuse to avoid these symptoms. Many people who use opioids self-treat withdrawal symptoms with a range of substances.
Alexander Preiss   +3 more
doaj   +1 more source

Characterization of cannabis withdrawal symptoms and serum levels of neurotransmitters among cannabis-dependent smokers during sustained abstinence within a controlled residential environment

open access: yesEuropean Psychiatry, 2023
Introduction Cannabis (aka marijuana) is the most frequently consumed illicit substance worldwide, and a subset of frequent cannabis smokers (up to 30%) develop dependence.
R. Sharma   +4 more
doaj   +1 more source

The relationship between addiction and hikikomori tendencies: a case-control study

open access: yesFrontiers in Psychiatry, 2023
AimThe present study examined the relationship between addiction and hikikomori (extreme social withdrawal) symptoms.MethodA group of clinically referred addiction patients (n = 31) and a group of age- and gender-matched non-clinical controls (n = 34 ...
Peter Muris   +4 more
doaj   +1 more source

The Effect of Co-occurring Substance Use on Gamma-hydroxybutyric Acid Withdrawal Syndrome

open access: yesJournal of Addiction Medicine, 2016
Gamma-hydroxybutyric acid (GHB) withdrawal is a complex syndrome which can be potentially life-threatening. Additionally, GHB-dependent patients frequently report co-occurring substance use of other psychoactive drugs. We assessed the add-on effect of co-use on GHB withdrawal symptoms.We conducted an open-label, pretest-posttest design study with 95 ...
Kamal, R.M.   +3 more
openaire   +5 more sources

Zaburzenia używania alkoholu: Czy nowe kryteria diagnostyczne implikują zmianę strategii terapeutycznych?

open access: yesAlcoholism and Drug Addiction, 2015
The aim of this paper is to present changes in diagnostic criteria of alcohol use disorders and some consequences concerning change to therapy and pharmacotherapy approaches.
Agnieszka Samochowiec   +3 more
doaj   +1 more source

Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant

open access: yesFrontiers in Psychiatry, 2021
Kratom or Mitragyna speciosa (Korth.) is an evergreen tree of the coffee family native to South-East Asia and Australasia. It is used by locals recreationally to induce stimulant and sedative effects and medically to soothe pain and opiate withdrawal ...
Alessandro E. Vento   +8 more
doaj   +1 more source

Modernizing Withdrawal Management Services

open access: yes, 2021
Alcohol, opioid, and stimulant withdrawal syndromes are serious clinical presentations, some of which can be life-threatening if untreated. Patients presenting with withdrawal syndromes offer an important opportunity for healthcare providers to ally in ...
Jan Klimas   +9 more
core   +1 more source

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