Results 61 to 70 of about 48,367 (253)

A Randomized Comparison of Lorazepam and Chlordiazepoxide in Patients With Uncomplicated Alcohol withdrawal

Archives of Mental Health, 2017
Background: Lorazepam (Ativan) and Chlordiazepoxide (Librium) are both popular treatments for alcohol-withdrawal syndrome. Nevertheless, there is little literature directly comparing the two drugs Aim: To compare the efficacy of Lorazepam and ...
Vishnu Gade, Lokesh Kumar Kalasapati, Ravali Reddy Kadari, Nidhi Tiyyagura, Pramod K R Mallepalli, C M Pavan Kumar   +5 more
doaj  

Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Type 2 diabetes (T2DM) heightens cognitive impairment risk, yet the mechanisms remain unclear. Hyperglycemia‐induced iron dysregulation in deep gray matter (DGM) nuclei may be a crucial mechanism. Purpose To investigate DGM iron deposition in T2DM using Quantitative Susceptibility Mapping (QSM) and determine its association with ...
Kun Wang, Jiahe Wang, Ziyu Diao, Xin Tan, Shijun Qiu, Jie An   +5 more
wiley   +1 more source

Ethanol Infusion for Alcohol Withdrawal Prophylaxis Does Not Cause Intoxication

Southwest Respiratory and Critical Care Chronicles, 2016
Objective: Alcohol Withdrawal Syndrome (AWS) remains a common problem, especially in trauma and surgical patients. An intravenous ethanol infusion protocol was developed at this institution and previously validated for AWS prophylaxis.
Robert Dillard, Tanis Welch, Senan Abdul-Hamed, Jennifer Kesey, Sharmila Dissanaike   +4 more
doaj  

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Qihuang Needle Therapy for Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background Motor symptoms in Parkinson's disease (PD) often respond incompletely to medication, highlighting the need for effective adjunctive therapies. Acupuncture may offer benefits, but high‐quality evidence for specialized techniques such as Qihuang needle therapy is lacking.
Wanqing Peng, Renhui Zhao, Ziting Huang, Jingpei Zhou, Yanning Liu, Zhijuan Liu, Xinyu Li, Jingjing Deng, Xubo Hong, Yanfang Chen, Nanbu Wang, Zhenhu Chen   +11 more
wiley   +1 more source

Global trends in epilepsy and the Chinese experience: Epidemiological transitions, underlying mechanisms, and integrated strategies (1990–2021)

Neuroprotection, EarlyView.
Epilepsy: Global Trends and the Chinese Experience (1990–2021). The infographic depicts (left) the global distribution of age‐standardized epilepsy DALY rates; (center) the triple inequality gap within China, including regional mortality disparities (9‐fold difference between western and eastern provinces), urban‐rural treatment gaps (60%–90%), and ...
Ting Chen, Mengqiao He, Sijia Basang, Hongyu Ren, Yutong Fu, Yu Li, Xin Shi, Lei Chen   +7 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Study of socio-economic, biochemical and clinical predictors of alcohol withdrawal and delirium tremens in patients of alcohol dependence in Indian population

Annals of Indian Psychiatry
Background: Alcohol withdrawal syndrome (AWS) is associated with morbidity and mortality. Assessment of factors affecting AWS will help in early diagnosis and initiation of appropriate treatment, hence improving the prognosis.
Parth Nagda, Devavrat Harshe, Ankit Halder, Navna Panchami Ravindran   +3 more
doaj   +1 more source

A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans.

PLoS ONE, 2010
Prolonged alcohol consumption in humans followed by abstinence precipitates a withdrawal syndrome consisting of anxiety, agitation and in severe cases, seizures.
Philippa Mitchell, Richard Mould, James Dillon, Steven Glautier, Ioannis Andrianakis, Christopher James, Amanda Pugh, Lindy Holden-Dye, Vincent O'Connor   +8 more
doaj   +1 more source

Impacts of Global Cannabis Policy Changes on Substance Use: A Systematic Review of Quasi‐Experimental Studies

The Milbank Quarterly, EarlyView.
Policy Points The liberalization of medical and recreational cannabis policies may increase cannabis initiation across age groups, with increased prevalence of cannabis use among young adults and adults and weaker effects among youth. Evidence also suggests increases in cannabis‐related health care utilization among adults.
SARAH B. WINDLE, PETER M. SOCHA, JASLEEN ARNEJA, SAM HARPER, GENEVIEVE GORE, GENEVIÉVE GARIÉPY, EVA GRAHAM, ANDREA BENEDETTI, ARIJIT NANDI   +8 more
wiley   +1 more source