Results 251 to 260 of about 1,178,781 (305)

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Underground Signals: The Ecological Power of Root Volatiles

Advanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao, Nanli Song, François Verheggen, Meritxell Pérez‐Hedo, Andrea Clavijo McCormick, Antonino Cusumano, Arthur de Fouchier, Bing Wang, Chen‐Zhu Wang, Emmanuelle Jacquin‐Joly, Gary W. Felton, Geoff M. Gurr, Hao Guo, Jiancai Li, Jin Zhang, Li Chen, Manqun Wang, Michele Ricupero, Peng Han, Peng He, Qi Yan, Qingbo Tang, Qingsong Liu, Shiheng An, Xiangbo Kong, Xiaoling Sun, Xueming Ren, Yuanyuan Song, Yang Liu, Yanhui Guo, Yunhe Li, Xiao Sun   +31 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

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Alcoholic extraction of oilseed with the aid of ultrasonics

Journal of the American Oil Chemists' Society, 1967
AbstractThe ultrasonic extraction of cottonseed with ethyl alcohol is studied. Several treating systems are evaluated with the seed in different positions in regard to the ultrasonic field. A calorimetric method was used for measuring the ultrasonic power to the treating vessels.
W F, Schurig, P, Sole
openaire   +2 more sources

Alcohol and Extract

1995
The alcohol content of a wine influences its stability as well as sensory properties. Wines are taxed, in large part, based on their alcohol levels. Careful monitoring of alcohol is important in stylistic wine production as well as in carrying out accurate fortifications, and in formulation of blends for bottling.
Bruce W. Zoecklein, Kenneth C. Fugelsang, Barry H. Gump, Fred S. Nury   +3 more
openaire   +1 more source

Pectin extraction in the presence of alcohols

Carbohydrate Polymers, 1989
Abstract A theoretical discussion of the extraction process and especially of the factors influencing extractant penetration in pectin-containing raw materials is presented. The necessity of adding surfactant in the pectin extraction is proved. Experiments were carried out with two types of apple pressings differing in anhydrouronic acid content and ...
N. Kirtchev, I. Panchev, Chr. Kratchanov
openaire   +1 more source

Simulated Dynamics and Control of an Extractive Alcoholic Fermentation

Applied Biochemistry and Biotechnology, 2000
In this study, we investigated the dynamics of a computer simulation of a continuous alcoholic fermentation process combined with a flash column under vacuum. The alcohol was partially extracted in order to maintain its concentration at about 40 kg/m3 in the fermentor.
A C, Costa, E C, Dechechi, F L, Silva, F, Maugeri, R, Maciel   +4 more
openaire   +2 more sources

Countercurrent Supercritical Fluid Extraction and Fractionation of Alcoholic Beverages

Journal of Agricultural and Food Chemistry, 2001
A procedure for the recovery of aromatic extracts from distilled alcoholic beverages by means of a countercurrent supercritical fluid extraction (CC-SFE) on a pilot plant scale is studied. The beverage is directly in contact with the carbon dioxide current in a packed column, and the extracts are recovered in two different fractionation cells, where ...
Señoráns, Francisco J., Ruiz-Rodríguez, Alejandro, Ibáñez, Elena, Tabera, Javier, Reglero, Guillermo   +4 more
openaire   +3 more sources

Water accumulation in the alcohol extraction of cottonseed

Journal of the American Oil Chemists' Society, 1993
The critical moisture content of cottonseed flakes extracted with an aqueous alcohol solvent can be defined as that flake moisture level at which the flakes lose no moisture during extraction. This study shows that the critical moisture content for aqueous ethanol (92%, w/w) is 3%. For aqueous isopropanol (88%, w/w) this value is 6%.
G. Abraham, R. J. Hron, M. S. Kuk, P. J. Wan   +3 more
openaire   +1 more source