Results 101 to 110 of about 75,203 (286)

Alcoholic hepatitis

, 2023
Alcoholic hepatitis should be suspected in patients with a recent onset of jaundice and with excessive chronic alcohol consumption. Diagnosis is based on clinical presentation and typical laboratory findings (aspartate aminotransférase (AST)/alanine ...
Moreno, Christophe, Degré, Delphine, Deltenre, Pierre   +2 more
core   +1 more source

Patients on statins with elevated transaminases: Frequency of follow‐up creatine kinase testing and gastroenterology referral

British Journal of Clinical Pharmacology, EarlyView.
Abstract Purpose To quantify how often creatine kinase (CK) is measured after newly elevated aminotransferases in statin users, and whether absent CK data are associated with gastroenterology (GI) referrals. Methods Retrospective chart review of adult outpatients on statins with a first alanine/aspartate aminotransferase (ALT/AST) elevation during a 5 ...
Faris Shweikeh, Anas Kartoumah, Rajshri Joshi, Anjali Nadihaan, Mohammed Mouchli, Inderprit Singh   +5 more
wiley   +1 more source

Trends in Alcoholic Hepatitis-related Hospitalizations, Financial Burden, and Mortality in the United States

, 2015
BACKGROUND: Alcoholic hepatitis (AH) is the most florid manifestation of alcoholic liver disease which accounts for significant morbidity, mortality, and financial burden.
Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium, Jinjuvadia, Raxitkumar, Liangpunsakul, Suthat   +2 more
core   +1 more source

Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis [PDF]

, 2010
Background: FibroTest (FT) is the most frequently used serum fibrosis marker and consists of an algorithm of five fibrosis markers (alfa2-macroglobulin, apolipoproteinA1, haptoglobin, GGT, bilirubin). The Enhanced Liver Fibrosis (ELF) test consists of an
Julie Parkes, Stefan Zeuzem, Herrmann, Eva, Friedrich-Rust, Mireen, William Rosenberg, Sarrazin, Christopher, Mireen Friedrich-Rust, Sarrazin, Christoph, Christoph Sarrazin, Parkes, Julie, Eva Herrmann, Rosenberg, William, Zeuzem, Stefan   +12 more
core   +1 more source

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

Exploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang, Yi Yang, Heng Li, Xiaolin Hu, Hui Xiao, Dou Wang, Sergio Benardini, Wei Gu, Yang Luo   +8 more
wiley   +1 more source

Alcoholic hepatitis masquerading as tumor infiltration: Reversibility after abstinence

Clinical Case Reports, 2019
A subset of patients with alcoholic hepatitis present with atypical imaging resembling hepatic tumor infiltration. Our case involves a patient who was initially thought to have multiple large hepatic metastases, ultimately found to have alcoholic ...
Adam B. Gluskin, Jeffrey M. Dueker, Mohamed El Hag, Kurian J. Puthenpurayil, Ramon Bataller   +4 more
doaj   +1 more source

Prevalência da doença hepática crónica em Portugal. A propósito de uma revisão efectuada numa unidade de hepatologia.

Acta Médica Portuguesa, 1996
The chronic elevation of Aminotransferases is one of the most frequent indications for percutaneous Liver Biopsy (LB). From a retrospective study of LB performed in the Hepatology liver Unit of Santa Maria Hospital, between 1989 and 1993, we correlated ...
A I Valente, A Almeida, A Gouveia, F Serejo, F Ramalho, A Baptista, A Saragoça, M C Moura   +7 more
doaj   +1 more source

Diagnosis and Severity Assessment of Alcohol-Related Liver Disease

The Korean Journal of Gastroenterology, 2020
A diagnosis of alcohol-related liver disease (ALD) requires information on the history of excessive alcohol consumption (average intake of 40 g or more in men and 20 g or more in women a day).
Eunju Kim, Seung Ha Park
doaj   +1 more source

Alcoholic hepatitis: The pivotal role of Kupffer cells. [PDF]

, 2015
Kupffer cells play a central role in the pathogenesis of alcoholic hepatitis (AH). It is believed that alcohol increases the gut permeability that results in raised levels of serum endotoxins containing lipopolysaccharides (LPS). LPS binds to LPS-binding
Hu, Robert W, Weeratunga, Ashley N, Hu, Richard, Suraweera, Duminda B, Pandol, Stephen J   +4 more
core   +1 more source