Results 81 to 90 of about 75,203 (286)

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

Morphometric study of hepatic ultrastructure in alcoholic hepatitis [PDF]

, 1987
We undertook a morphometric analysis of hepatocellular organelles in an attempt to correlate their changes with the clinical stages of patients.with alcoholic hepatitis.
Rabin, L., Mendenhall, C.L., Veterans Administration Cooperative Study Group on Alcoholic Hepatitis, Marquet, G., Murphy, D.P., Chedid, A., Chen, T.S.   +6 more
core  

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

Changes in the fecal bacterial microbiota associated with disease severity in alcoholic hepatitis patients

Gut Microbes, 2020
Background and Aims Alcoholic hepatitis is the most severe form of alcohol-related liver disease. While the gut microbiome is known to play a role in disease development and progression, less is known about specific compositional changes of the gut ...
Sonja Lang, Bradley Fairfied, Bei Gao, Yi Duan, Xinlian Zhang, Derrick E. Fouts, Bernd Schnabl   +6 more
doaj   +1 more source

The National Clinical Database Risk Calculator and the 5‐Item Modified Frailty Index Predict the Development of Postoperative Delirium After Surgery for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that combining the NCD Risk Calculator with the mFI‐5 enables more precise stratification of postoperative delirium risk in patients undergoing surgery for HCC. Patients classified as high risk by the combined model showed a markedly higher incidence of delirium than those in the intermediate‐ and low‐risk groups.
Kiyotaka Hosoda, Akira Shimizu, Koji Kubota, Tsuyoshi Notake, Hiroki Sakai, Kentaro Yoshikawa, Tomohiko Ikehara, Hikaru Hayashi, Koya Yasukawa, Yuji Soejima   +9 more
wiley   +1 more source

High serum N-terminal propeptide of procollagen type III concentration is associated with liver diseases

Gastroenterology Review, 2017
Introduction : N-terminal propeptide of procollagen type III (PIIINP) is generated during the synthesis of type III collagen. PIIINP can be measured in the serum as an indicator of liver fibrosis and cirrhosis.
Monika Gudowska, Ewa Gruszewska, Anatol Panasiuk, Bogdan Cylwik, Magdalena Swiderska, Robert Flisiak, Maciej Szmitkowski, Lech Chrostek   +7 more
doaj   +1 more source

THE TREATMENT OF ALCOHOLIC HEPATITIS [PDF]

Alcohol and Alcoholism, 1996
Alcoholic hepatitis is a precirrhotic lesion; it develops in only a minority of chronic alcohol abusers even after decades of abuse. The clinical spectrum of disease varies from asymptomatic hepatomegaly to florid hepatocellular failure with gastrointestinal bleeding and hepatic encephalopathy.
openaire   +2 more sources

The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies. [PDF]

, 2011
AIMS: Non-alcoholic fatty liver disease (NAFLD) is a complex disease trait where genetic variations and environment interact to determine disease progression.
Patch, Julia, J. Patch, Ann K. Daly, J. B. S. Leathart, Quentin M. Anstee, Julian B.S. Leathart, Julia Patch, Christopher P. Day, Nobili, Valerio, Valerio Nobili, Anna Fracanzani, Silvia Fargion, Q. M. Anstee, Leathart, Julian B S, Day, Christopher P, Daly, Ann K, L. Valenti, Ahmad Al-Serri, S. Fargion, Paola Dongiovanni, Al Serri, Ahmad, Anstee, Quentin M, Fracanzani, Anna, Dongiovanni, Paola, C. P. Day, A. Fracanzani, A. Al Serri, V. Nobili, A. K. Daly, Valenti, Luca, P. Dongiovanni, Luca Valenti, Fargion, Silvia   +32 more
core   +1 more source

Multifactor Risk Stratification for Post‐Transplant Alcohol Relapse Using Abstinence, Psychosocial, and Socioeconomic Factors

Annals of Gastroenterological Surgery, EarlyView.
Alcohol relapse after liver transplantation is difficult to predict using abstinence duration alone. We developed a multifactor model integrating abstinence duration, psychosocial risk (SIPAT), and socioeconomic context (AUC 0.70). This approach may support individualized risk assessment and tailored follow‐up intensity; external validation is needed ...
Ayato Obana, Garren Montgomery, Miho Akabane, Matthew Hamilton, Navdeep Singh, Musab Alebrahim, Austin Schenk, Sylvester Black, Kenneth Washburn, Khalid Mumtaz   +9 more
wiley   +1 more source

Unusual Infections Complicating the Use of Steroids with Severe Alcoholic Hepatitis: Report of 2 Cases

Canadian Journal of Gastroenterology, 1995
Corticosteroid therapy for acute alcoholic hepatitis has been demonstrated to enhance survival in patients who are encephalopathic, and who do not have renal failure or gastrointestinal bleeding.
Vitor Arantes, Pina Michieletti, Ross Cameron, Jenny Heathcote, Morris Sherman   +4 more
doaj   +1 more source