Results 41 to 50 of about 115,592 (248)

Alcoholic Liver Disease in the Asian–Pacific Region with High Prevalence of Chronic Viral Hepatitis

Journal of Medical Ultrasound, 2016
The hospitalized cases and mortality from alcoholic liver disease (ALD) are increasing in Taiwan and worldwide. Meanwhile, the Asia–Pacific region also has a high prevalence of hepatitis B virus (HBV) and hepatocellular carcinoma (HCC).
Sien-Sing Yang
doaj   +1 more source

Comparison of TNF-α Levels in Alcoholic Liver Disease Patients with and without Hepatitis: A Cross-sectional Study in Coastal Karnataka, India [PDF]

National Journal of Laboratory Medicine
Introduction: Alcohol-induced liver injury triggers inflammatory reactions through pro-inflammatory cytokine Tumour Necrosis Factor-α (TNF-α). The estimation of TNF-α would provide valuable information on the degree of activation of immune system and ...
TM Anuraghi, Krishnamoorthy Srilatatha, Jinsha Fathima, Yassir Shaheena   +3 more
doaj   +1 more source

Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co‐Metabolism in Patients With Alcoholic Hepatitis

Hepatology Communications, 2020
Alcohol‐related liver disease is a major public health burden, and the gut microbiota is an important contributor to disease pathogenesis. The aim of the present study is to characterize functional alterations of the gut microbiota and test their ...
Bei Gao, Yi Duan, Sonja Lang, Dinesh Barupal, Tsung‐Chin Wu, Luis Valdiviez, Bryan Roberts, Ying Yng Choy, Tong Shen, Gregory Byram, Ying Zhang, Sili Fan, Benjamin Wancewicz, Yan Shao, Kevin Vervier, Yanhan Wang, Rongrong Zhou, Lu Jiang, Shilpa Nath, Rohit Loomba, Juan G. Abraldes, Ramon Bataller, Xin M. Tu, Peter Stärkel, Trevor D. Lawley, Oliver Fiehn, Bernd Schnabl   +26 more
doaj   +1 more source

Alcoholic Hepatitis: A Review [PDF]

Alcohol and Alcoholism, 2019
AbstractAlcoholic liver disease (ALD) represents a spectrum of injury, ranging from simple steatosis to alcoholic hepatitis to cirrhosis. Regular alcohol use results in fatty changes in the liver which can develop into inflammation, fibrosis and ultimately cirrhosis with continued, excessive drinking.
Nooshin, Hosseini, Julia, Shor, Gyongyi, Szabo   +2 more
openaire   +2 more sources

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian, An-Ming Yang, Bernd Schnabl, Bode, Chien-Sheng Chen, Claus Hellerbrand, Cristina Llorente, Derrick E. Fouts, Ece A. Mutlu, Fettweis, Fouts, Gordon D. Brown, Guadalupe Garcia-Tsao, Hal M. Hoffman, Jun Xu, Karen Beeri, Katrin Hochrath, Kelvin Moncera, Kim Freese, Lee, Lirui Wang, Liu, Manolito G. Torralba, Peng Chen, Peter Stärkel, Phillipp Hartmann, Ramon Bataller, Samuel B. Ho, Sena Bluemel, Serene M.L. Lee, Sokol, Tatiana Kisseleva, Tatsuo Inamine, Wagner, Wajahat Z. Mehal, Yamahiro, Yang, Yukinori Koyama   +37 more
core   +3 more sources

Management of alcoholic hepatitis [PDF]

Drug and Therapeutics Bulletin, 2003
About 5,000 people die each year from chronic liver disease in England and Wales alone.1 In many patients, the liver injury is due to chronic excessive alcohol consumption and manifests as alcoholic hepatitis (an acute inflammation of the liver), cirrhosis, or alcoholic hepatitis superimposed on a background of cirrhosis.2 Mild alcoholic hepatitis may ...
openaire   +4 more sources

Acute Alcoholic Hepatitis

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2017
Objective: To examine the natural history of acute alcoholic hepatitis (AH) and identify predictors of mortality for AH using data from a prospective multicenter observational study.
Spencer Lourens, PhD, Dharma B. Sunjaya, MD, Ashwani Singal, MD, Suthat Liangpunsakul, MD, MPH, Puneet Puri, MD, Arun Sanyal, MD, Xiaowei Ren, MS, Gregory J. Gores, MD, Svetlana Radaeva, PhD, Naga Chalasani, MD, David W. Crabb, MD, Barry Katz, PhD, Patrick S. Kamath, MD, Vijay H. Shah, MD, David Crabb, MD, Naga Chalasani, MD, Suthat Liangpunsakul, MD, Barry Katz, PhD, Spencer Lourens, PhD, Andy Borst, BS, Ryan Cook, MPH, Andy Qigui Yu, PhD, David Nelson, PhD, Romil Saxena, MD, Sherrie Cummings, RN, Megan Comerford, BS, Lakye Edwards, BS, Vijay H. Shah, MD, Gregory Gores, MD, Patrick S. Kamath, MD, Vikas Verma, PhD, Sarah Wilder, RN, BSN, Amy Olofson, RN, Amanda Schimek, Arun Sanyal, MD, Puneet Puri, MD, Susan Walker, RN, MSN, Svetlana Radaeva, PhD, Andras Orosz, PhD   +38 more
doaj   +1 more source

Machine Learning Applied to Omics Datasets Predicts Mortality in Patients with Alcoholic Hepatitis

Metabolites, 2022
Alcoholic hepatitis is a major health care burden in the United States due to significant morbidity and mortality. Early identification of patients with alcoholic hepatitis at greatest risk of death is extremely important for proper treatments and ...
Bei Gao, Tsung-Chin Wu, Sonja Lang, Lu Jiang, Yi Duan, Derrick E. Fouts, Xinlian Zhang, Xin-Ming Tu, Bernd Schnabl   +8 more
doaj   +1 more source

Specificities of lipotoxicity of free fatty acids and cytokine profile in patients with chronic diffuse liver diseases

Regulatory Mechanisms in Biosystems, 2021
Non-alcoholic fatty liver disease is an important cause of global liver disease characterized by diffuse hepatocytes with hepatocellular ballooning, intrahepatic inflammation and progressive fibrosis.
V. I. Didenko, I. A. Klenina, О. M. Tatarchuk, O. I. Hrabovska, O. P. Petishko   +4 more
doaj   +1 more source

Gut-microbiota prompt activation of natural killer cell on alcoholic liver disease

Gut Microbes, 2023
The liver is rich in innate immune cells, such as natural killer (NK) cells, natural killer T cells, and Kupffer cells associated with the gut microbiome. These immune cells are dysfunctional owing to alcohol consumption.
Jung A Eom, Jin-Ju Jeong, Sang Hak Han, Goo Hyun Kwon, Kyeong Jin Lee, Haripriya Gupta, Satya Priya Sharma, Sung-Min Won, Ki-Kwang Oh, Sang Jun Yoon, Hyun Chae Joung, Kyung Hwan Kim, Dong Joon Kim, Ki Tae Suk   +13 more
doaj   +1 more source