Results 11 to 20 of about 5,655,373 (303)
Autophagy in non-alcoholic fatty liver disease and alcoholic liver disease [PDF]
Autophagy is an evolutionarily conserved intracellular degradative function that is important for liver homeostasis. Accumulating evidence suggests that autophagy is deregulated during the progression and development of alcoholic and non-alcoholic liver ...
Bilon Khambu +4 more
doaj +6 more sources
Background:Non-alcoholic fatty liver disease (NAFLD) is a global health problem affecting more than a quarter of the entire adult population. Both monocytes and high-density lipoprotein cholesterol (HDL-C) were found to participate in the progression of ...
Liping Wang +8 more
doaj +1 more source
Important mechanisms responsible for alcohol-induced liver injury include mitochondrial damage and loss of ATP, formation of acetaldehyde-and other aldehyde-protein adducts, release of reactive oxygen species (ROS) from mitochondrial electron transfer chain, CYP2E1 , and activated Kupffer cells (KCs); weakening of antioxidant defense systems; and ...
L, Lumeng, D W, Crabb
openaire +5 more sources
To study the role of magnesium and Gamma- glutamyl transferases in alcoholic liver disease
Aim: To study the role of magnesium and gamma- glutamyl transferases in alcoholic liver disease. Objectives: (1) To estimate serum magnesium and serum glutamyl-transferases (GGT) in alcoholic liver disease.
Kapila Gaikwad +2 more
doaj +1 more source
Alcoholic liver disease: Current insights into cellular mechanisms [PDF]
Alcoholic liver disease (ALD) due to chronic alcohol consumption is a significant global disease burden and a leading cause of mortality. Alcohol abuse induces a myriad of aberrant changes in hepatocytes at both the cellular and molecular level. Although
Patel, V. +2 more
core +1 more source
Aim To estimate the risk of cancer incidence and mortality among patients with alcoholic liver disease in South Korea. Methods A matched cohort study was conducted, including 1,042,185 men (alcoholic liver disease cases: 208,437; controls: 833,748) and ...
Thi Phuong Thao Tran +3 more
doaj +1 more source
Correlates of ultrasound diagnosed non alcoholic fatty liver disease in Indian adults with features of metabolic syndrome [PDF]
Because of its complex pathogenesis and scarcity of approved therapies, non-alcoholic fatty liver disease is considered as one of the major challenge before mankind. Literature suggests that non-alcoholic fatty liver disease will replace Hepatitis C as a
Imran Nazir Salroo +3 more
doaj +1 more source
Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E. +70 more
core +1 more source
Burden of Alcoholic Liver Disease in a Tertiary Care Center: A Descriptive Cross-sectional Study
Introduction: Alcoholic liver disease is a serious health problem related to an unhealthy lifestyle. The three most widely recognized forms of alcoholic liver disease are alcoholic fatty liver, acute alcoholic hepatitis, and alcoholic cirrhosis. The main
Sikha Rizal +2 more
doaj +1 more source
Insulin sensitisers in the treatment of non-alcoholic fatty liver disease : a systematic review [PDF]
Non-alcoholic fatty liver disease (NAFLD) is closely linked with obesity and the prevalence of NAFLD is about 17% to 33% in the Western world. There is a strong association of NAFLD with insulin resistance and, hence, insulin sensitisers have been tried.
C Clar +21 more
core +1 more source

