Results 51 to 60 of about 180,858 (308)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Primary care and referring physician perspectives on non-alcoholic fatty liver disease management: a nationwide survey

Therapeutic Advances in Gastroenterology, 2021
Introduction: The optimal approach to screening and risk stratification for non-alcoholic fatty liver disease is challenging given disease burden and variable progression. The aim of this study was to assess primary care physician and referring physician
Naba Saeed, Lisa M. Glass, Heba Habbal, Asad Mahmood, David Sengstock, Sameer D. Saini, Monica A. Tincopa   +6 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies. [PDF]

, 2011
AIMS: Non-alcoholic fatty liver disease (NAFLD) is a complex disease trait where genetic variations and environment interact to determine disease progression.
Patch, Julia, J. Patch, Ann K. Daly, J. B. S. Leathart, Quentin M. Anstee, Julian B.S. Leathart, Julia Patch, Christopher P. Day, Nobili, Valerio, Valerio Nobili, Anna Fracanzani, Silvia Fargion, Q. M. Anstee, Leathart, Julian B S, Day, Christopher P, Daly, Ann K, L. Valenti, Ahmad Al-Serri, S. Fargion, Paola Dongiovanni, Al Serri, Ahmad, Anstee, Quentin M, Fracanzani, Anna, Dongiovanni, Paola, C. P. Day, A. Fracanzani, A. Al Serri, V. Nobili, A. K. Daly, Valenti, Luca, P. Dongiovanni, Luca Valenti, Fargion, Silvia   +32 more
core   +1 more source

Diagnosis of Non-alcoholic fatty liver disease

Journal of Pathology of Nepal, 2016
Non Alcoholic Fatty Liver Disease is the deposition of fat in liver in absence of excessive of alcohol consumption. Non Alcoholic Fatty Liver Disease ranges from simple steatosis to Nonalcoholic steatohepatitis and cirrhosis.
Geetika K.C.
doaj   +1 more source

The effect of a high-intensity interval training with Portulaca oleracea supplementation on Irisin and TLR4 in the liver tissue of rats with non-alcoholic fatty liver disease [PDF]

مجله علوم پزشکی فیض (پیوسته), 2023
Background: Lifestyle modification through dietary interventions and exercise training is still one of the most effective ways to treat non-alcoholic fatty liver disease.
Majid Farah Nia, Mohammad Raza Hosseinabadi, Mehdi Zarei, Mahmood Soltani   +3 more
doaj   +2 more sources

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Lifestyle modification in NAFLD/NASH: Facts and figures

JHEP Reports, 2019
Summary: The development of non-alcoholic fatty liver disease is closely linked to lifestyle factors, namely excessive caloric intake coupled with reduced physical activity and exercise. This review aims to examine the evidence behind lifestyle change as
Kate Hallsworth, Leon A. Adams
doaj   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

The Prevalence of Metabolically associated Steatotic Liver Disease in Patients with Inflammatory Bowel Disease in Erbil City

Advanced Medical Journal
Background and Objective: The non-alcoholic fatty liver disease is prevalent in about one-fourth of the world population. The link between inflammatory bowel diseases and non-alcoholic fatty liver disease has been of great concern in last decades.
Rieber Abdulrahman Kareem, Abdullah Saeed Ibrahim, Altun Mahmud Saleh   +2 more
doaj   +1 more source