Results 91 to 100 of about 1,287,361 (347)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Study of pyridine-mediated electrochemical reduction of CO2 to methanol at high CO2 pressure [PDF]

, 2016
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim The recently proposed highly efficient route of pyridine-catalyzed CO 2 reduction to methanol was explored on platinum electrodes at high CO 2 pressure.
Barton, Barton Cole, Barton Cole, Bocarsly, Boston, Costentin, de Tacconi, Ertem, Hori, Keets, Keith, Keith, Krauskopf, Lebègue, Li, Li, Li, Liao, Lim, Lucio, Lukaszewski, Mairanovskii, Mairanovskii, Morris, Nicholson, Podlovchenko, Polievktov, Portenkirchner, Rodes, Schulz, Seshadri, Shannon, Tossell, Treimer, Wang, Yan, Yang, Yuan, Zeitler, Zeng   +39 more
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Hydration of methanol in water. A DFT-based molecular dynamics study [PDF]

, 2000
We studied the hydration of a single methanol molecule in aqueous solution by first-principle DFT-based molecular dynamics simulation. The calculations show that the local structural and short-time dynamical properties of the water molecules remain ...
Baerends, Barnett, Becke, Benedict, Car, Curioni, Evert Jan Meijer, Ferrario, González, Guerra, Hohenberg, Hoover, Jorgensen, Kohn, Laaksonen, Lee, Meijer, Nosé, Nosé, Pálinkás, Schütz, Silvestrelli, Soper, Sprik, Tanaka, te Velde, Titus S. van Erp, Troullier   +27 more
core   +3 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Bases of inorganic and organic chemistry [PDF]

, 2016
Stated fundamental theoretical principles of general, inorganic and organic chemistry and analyzed the reactivity of the most important classes of inorganic and organic substances. A multivariate tasks and exercises for classroom and independent work are
Alami, D., Slavkova, M., Ved, M.
core  

Microemulsion breakdown by pervaporation technique: Effect of the alkyl chain length of n-alkanol, a cosurfactant of the microemulsion [PDF]

, 2007
Two sets of microemulsions, cyclohexane- and water-rich ones, were prepared with the following n-alkanols as cosurfactants: n-propanol, n-butanol, n-pentanol, and n-hexanol.
Canselier, Jean-Paul, Hadj-Ziane-Zafour, Amel, Moulay, Saâd   +2 more
core   +2 more sources

Metallaphotoredox-enabled deoxygenative arylation of alcohols

Nature, 2021
Zhe Dong, D. MacMillan
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source