Results 131 to 140 of about 256,760 (299)
, 2013 Betaine aldehyde dehydrogenase has been purified to homogeneity from rat liver mitochondria. The properties of betaine aldehyde dehydrogenase were similar to those of human cytoplasmic E3 isozyme in substrate specificity and kinetic constants for ...
Pietruszko, Regina +1 more
core
, 1959 Durch Umsetzung von Fulvenen mit Phosphoroxychlorid in Dimethylformamid erhält man in guten Ausbeuten Fulven-aldehyde, von denen bisher kein Vertreter bekannt ...
Hafner, Klaus, Vöpel, K. H.
core +1 more source
Advanced Science, EarlyView.This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng +9 more
wiley +1 more source
Advanced Science, EarlyView.A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu +11 more
wiley +1 more source
Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction
Advanced Science, EarlyView.Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen +5 more
wiley +1 more source
Advanced Science, EarlyView.In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang +13 more
wiley +1 more source
Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy
Advanced Science, EarlyView.Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan +14 more
wiley +1 more source
Thermal stability of collagen treated with phenol-aldehyde Matrices
工程科学与技术, 2009 :The interactions of collagen, with polyphenol and aldehyde, have been investigated using a number of analytical techniques such as DSC and size distribution. The collagen was simulated with hide powder.
Chen Hui, 李铠, 邰双喜
doaj
, 2010 碩士酵母菌醛類去氫酶4（YOR374w）是一種位在粒線體內的去氫酶，需要鉀離子的活化，以及NAD+或NADP+當輔酶，在乙醇的代謝途徑扮演很重要的角色，尤其是以乙醇當碳源的環境下。為了了解醛類去氫酶對於其他不同代謝途徑是否有影響，經由選殖出正確ALD4基因，再利用大腸桿菌大量的表現出ald4p，透過管柱層析純化之後，對許多不同的受質做活性分析。在酵母菌的泛酸生合成途徑中，3-aminopropanal氧化成beta-alanine是重要的一個反應，而glycine betaine是一種滲透壓保護劑 ...
陳俊傑; Chen, Jyun-jie
core
Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics
Advanced Science, EarlyView.DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley +1 more source