Results 141 to 150 of about 228,734 (312)
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger +9 more
wiley +1 more source
This account briefly describes the authors' recent efforts to develop the catalytic coupling of aldehyde, alkyne, and amiine, as well as asymmetric catalytic coupling of aldehyde, alkyne, and amine.[...
Li, Zigang, Wei, Chunmei, Li, Chao-Jun
core +1 more source
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis +32 more
wiley +1 more source
Ethnopharmacological relevance: COX-2 has been considered as a potent molecular target for prevention and therapy of depression. However, a recent study showed that COX-2 inhibitor does not improve depressive symptoms in persons aged 70 and over ...
Yang, Yuan-Xiao +3 more
core
Arylation of Aldehyde Homoenolates with Aryl Bromides
A mild palladium catalyzed coupling of reactive aldehyde homoenolates with aryl bromides is described. Aldehyde homoenolates are generated by ring opening of cyclopropanols via a C–C cleavage step.
Kevin Cheng (836757) +1 more
core +1 more source
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo +9 more
wiley +1 more source
Preparation of polycrotonic aldehyde
Croton aldehyde (2-butenal) is a reactive compound. NaOH and, in the second experiment, KOH were used to get polycrotonic aldehyde. The dependence of alkali concentration and amount of water on the yield of polymerization products was revealed.
Shavkat Oblokulov
core +1 more source
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas +6 more
wiley +1 more source
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci +13 more
wiley +1 more source
Aldehyde oxidase (AOX) metabolizes various compounds, but its regulation is not well understood. Retinoic acid (RA) has two main isomers: all-trans RA (ATRA), which binds to retinoic acid receptor (RAR), and 9-cis-RA, which binds to RAR and retinoid X ...
Allen, Erica
core

