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Aldehyde toxicity and metabolism: the role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis

Drug metabolism reviews (Softcover ed.), 2019
Aldehydes are carbonyl compounds found ubiquitously in the environment, derived from both natural and anthropogenic sources. As the aldehydes are reactive species, therefore, they are generally toxic to the body.
Amaj Ahmed Laskar, H. Younus
semanticscholar   +1 more source

Crystalline Covalent Triazine Frameworks by In Situ Oxidation of Alcohols to Aldehyde Monomers.

Angewandte Chemie, 2018
Covalent triazine frameworks (CTFs) with aromatic triazine linkages have recently received increasing interest for various applications because of their rich nitrogen content and high chemical stability.
Manying Liu   +6 more
semanticscholar   +1 more source

Rapid Organocatalytic Aldehyde‐Aldehyde Condensation Reactions

European Journal of Organic Chemistry, 2007
AbstractWe report the results of the systematic optimization of the α‐methylenation of aldehydes with aqueous formaldehyde. A simple combination of a secondary amine catalyst and a weak acid co‐catalyst has been identified, allowing access to α‐substituted acroleins in a matter of minutes.
Anniina Erkkilae, Petri M. Pihko
openaire   +1 more source

ChemInform Abstract: Aldehydes: Alkyl Aldehydes

ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
K. E. B. PARKES, S. K. RICHARDSON
openaire   +1 more source

Aldehyde Inhibitors of Aldehyde Dehydrogenases

1999
Aldehyde dehydrogenases catalyze aldehyde dehydrogenation as well as ester hydrolysis. Nitrate esters e.g. isosorbide nitrates and nitroglycerin inhibit the enzyme. Mechanism of inhibition which involves aldehyde dehydrogenase catalyzed formation of a reactive species (Mukerjee and Pietruszko, 1994), which inactivates the enzyme via covalent bond ...
R, Pietruszko   +5 more
openaire   +2 more sources

Synthesis of Chiral Aldehyde Catalysts via Pd-Catalyzed Atroposelective C-H Naphthylation.

Angewandte Chemie, 2019
Chiral aldehyde catalysis opens new avenues for the activation of simple amines. However, the lack of easy access to structurally diverse chiral aldehyde catalysts has hampered the development of this cutting-edge field.
Gang Liao   +5 more
semanticscholar   +1 more source

Role of Aldehyde Dehydrogenases in Physiopathological Processes.

Chemical Research in Toxicology, 2019
Many different diseases are associated with oxidative stress. One of the main consequences of oxidative stress at the cellular level is lipid peroxidation, from which toxic aldehydes may be generated.
J. Rodríguez-Zavala   +3 more
semanticscholar   +1 more source

Aldehydes: Alkyl Aldehydes

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Chiral Aldehyde Catalysis for the Catalytic Asymmetric Activation of Glycine Esters.

Journal of the American Chemical Society, 2018
Chiral aldehyde catalysis is uniquely suitable for the direct asymmetric α-functionalization of N-unprotected amino acids, because aldehydes can reversibly form imines. However, there have been few successful reports of these transformations.
Wei Wen   +6 more
semanticscholar   +1 more source

Aldehydes: Aryl and Heteroaryl Aldehydes

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

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