Results 1 to 10 of about 69,081 (115)

The aldehyde dehydrogenase superfamilies: correlations and deviations in structure and function [PDF]

Applied Microbiology and Biotechnology
Aldehyde dehydrogenases participate in many biochemical pathways, either by degrading organic substrates via organic acids or by producing reactive aldehyde intermediates in many biosynthetic pathways, and are becoming increasingly important for ...
Johann Heider, Dominik Hege
doaj   +2 more sources

Salivary Aldehyde Dehydrogenase: Activity Towards Aromatic Aldehydes and Comparison With Recombinant ALDH3A1

Molecules, 2009
A series of aromatic aldehydes was examined as substrates for salivary aldehyde dehydrogenase (sALDH) and the recombinant ALDH3A1. Para-substituted benzaldehydes, cinnamic aldehyde and 2-naphthaldehydes were found to be excellent substrates, and kinetic ...
Monika Pietrzak, Piotr Wroczyński, Renata Wolinowska   +2 more
exaly   +3 more sources

Cloning and Functional Analysis of the Aldehyde Dehydrogenase Gene VvALDH in the IAA Synthesis Pathway of Volvariella volvacea [PDF]

Journal of Fungi
Volvariella volvacea, the Chinese mushroom, is a high-temperature grass-rot fungus with great production potential, yet its low yield limits industrial development.
Mingjuan Mao, Lijuan Hou, Lin Ma, Ning Jiang, Jinsheng Lin, Shaoxuan Qu, Huiping Li, Ping Xu, Di Liu, Wei Ji   +9 more
doaj   +2 more sources

Robust assembly of the aldehyde dehydrogenase Ald4p in Saccharomyces cerevisiae [PDF]

Biology Open, 2023
Channarong Nasalingkhan, Naraporn Sirinonthanawech, Chalongrat Noree   +2 more
doaj   +2 more sources

ALDH2 attenuates myocardial pyroptosis through breaking down Mitochondrion-NLRP3 inflammasome pathway in septic shock

Frontiers in Pharmacology, 2023
Cell survival or death is critical for cardiac function. Myocardial pyroptosis, as a newly recognized programmed cell death, remains poorly understood in sepsis.
Ying Zhang, Ying Zhang, Ying Zhang, Ying Zhang, Ying Lv, Ying Lv, Ying Lv, Ying Lv, Qingju Zhang, Qingju Zhang, Qingju Zhang, Qingju Zhang, Xingfang Wang, Xingfang Wang, Xingfang Wang, Xingfang Wang, Qi Han, Qi Han, Qi Han, Qi Han, Yan Liang, Yan Liang, Yan Liang, Yan Liang, Simeng He, Simeng He, Simeng He, Simeng He, Qiuhuan Yuan, Qiuhuan Yuan, Qiuhuan Yuan, Qiuhuan Yuan, Jiaqi Zheng, Jiaqi Zheng, Jiaqi Zheng, Jiaqi Zheng, Changchang Xu, Changchang Xu, Changchang Xu, Changchang Xu, Xiangxin Zhang, Xiangxin Zhang, Xiangxin Zhang, Xiangxin Zhang, Zichen Wang, Zichen Wang, Zichen Wang, Zichen Wang, Huaxiang Yu, Huaxiang Yu, Huaxiang Yu, Huaxiang Yu, Li Xue, Li Xue, Li Xue, Li Xue, Jiali Wang, Jiali Wang, Jiali Wang, Jiali Wang, Feng Xu, Feng Xu, Feng Xu, Feng Xu, Jiaojiao Pang, Jiaojiao Pang, Jiaojiao Pang, Jiaojiao Pang, Yuguo Chen, Yuguo Chen, Yuguo Chen, Yuguo Chen   +71 more
doaj   +1 more source

Increased salivary aldehyde dehydrogenase 1 in non-reticular oral lichen planus [PDF]

Anais Brasileiros de Dermatologia, 2017
: Background: Oral lichen planus is a potentially malignant disorder. One of the malignant transformation markers is cancer stem cells. One of the proposed marker for the detection of cancer stem cells's in head and neck cancer is aldehyde dehydrogenase.
Arash Mansourian, Najmeh Shanbehzadeh, Seyed Javad Kia, Mahdieh-Sadat Moosavi   +3 more
doaj   +2 more sources

Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3

Communications Biology, 2022
Three X-ray structures are presented of human aldehyde dehydrogenase family 1 member A3 (ALDH1A3), a potential cancer stem cell biomarker (alone, with NAD+ and with ATP) and structure determination performed using molecular replacement.
Albert Castellví, Raquel Pequerul, Vito Barracco, Judith Juanhuix, Xavier Parés, Jaume Farrés   +5 more
doaj   +1 more source

ALDH3B1 Is an Independent Prognostic Biomarker of Lung Adenocarcinoma

Technology in Cancer Research & Treatment, 2020
Background: Lung cancer is the leading cause of cancer-related death, and adenocarcinoma is the most common type of lung cancer. Although emerging evidence implicates the role of several aldehyde dehydrogenases in cancer progression, the expression and ...
Hongmei Sun MD, Mingying Zhang MD, Li Li MD, Zongwen Huang MD   +3 more
doaj   +1 more source

N-Substituted 2-(Benzenosulfonyl)-1-Carbotioamide Derivatives Exert Antimicrobial and Cytotoxic Effects via Aldehyde Dehydrogenase Pathway: Synthesis, In Silico and In Vitro Studies

Pharmaceuticals, 2023
A series of N-Substituted 2-(benzenosulfonyl)-1-carbotioamide derivatives (WZ1–WZ4) were synthesized and characterized using spectral methods. A comprehensive activity study was performed for each compound.
Lucja Walczak-Nowicka, Anna Biernasiuk, Wojciech Ziemichód, Zbigniew Karczmarzyk, Mateusz Kwaśnik, Paweł Kozyra, Waldemar Wysocki, Agnieszka Stenzel-Bembenek, Dorota Kowalczuk, Mariola Herbet, Monika Pitucha   +10 more
doaj   +1 more source

Aldehyde Dehydrogenase Diversity in Azospirillum Genomes

Diversity, 2023
Aldehyde dehydrogenases (ALDHs) are indispensable enzymes that play a pivotal role in mitigating aldehyde toxicity by converting them into less reactive compounds.
Ricardo Cuatlayotl-Olarte, María Luisa Xiqui-Vázquez, Sandra Raquel Reyes-Carmona, Claudia Mancilla-Simbro, Beatriz Eugenia Baca, Alberto Ramírez-Mata   +5 more
doaj   +1 more source