Results 11 to 20 of about 262,052 (188)

Human aldehyde dehydrogenase E3 isozyme is a betaine aldehyde dehydrogenase

Biochemical and Biophysical Research Communications, 2013
The E3 isozyme of human aldehyde dehydrogenase (EC 1.2.1.3), with broad substrate specificity, which also catalyzes dehydrogenation of 4-aminobutyraldehyde, was purified and sequenced recently (1,3).
Pietruszko, Regina, Chern, Ming-kai; Pietruszko, Regina   +1 more
core   +3 more sources

Aldehyde dehydrogenase in tobacco pollen [PDF]

Plant Molecular Biology, 1997
Acetaldehyde is one of the intermediate products of ethanolic fermentation, which can be reduced to ethanol by alcohol dehydrogenase (ADH). Alternatively, acetaldehyde can be oxidized to acetate by aldehyde dehydrogenase (ALDH) and subsequently converted
op den Camp, Roel GL, Kuhlemeier, Cris
core   +6 more sources

The diagnostic value of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) measurement in the sera of patients with brain tumor

Archives of Medical Science, 2017
Introduction: Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) exist in the brain. Alcohol dehydrogenase and ALDH are also present in brain tumor cells.
Wojciech Jelski, Magdalena Laniewska-Dunaj, Karolina Orywal, Jan Kochanowicz, Robert Rutkowski, Maciej Szmitkowski   +5 more
doaj   +2 more sources

Activity of the cytosolic enzymes of endogenous aldehydes catabolism under the conditions of different nutrients content in a diet

Біологія тварин, 2022
The research was conducted to study the activity of aldehyde dehydrogenase (EC 1.2.1.3) and aldehyde reductase (EC 1.1.1.21), the levels of TBA reactive substances and protein carbonyl derivates in the cytosolic fraction of rat liver under the conditions
O. M. Voloshchuk, T. V. Luchyk
doaj   +1 more source

ALDH3B1 Is an Independent Prognostic Biomarker of Lung Adenocarcinoma

Technology in Cancer Research & Treatment, 2020
Background: Lung cancer is the leading cause of cancer-related death, and adenocarcinoma is the most common type of lung cancer. Although emerging evidence implicates the role of several aldehyde dehydrogenases in cancer progression, the expression and ...
Hongmei Sun MD, Mingying Zhang MD, Li Li MD, Zongwen Huang MD   +3 more
doaj   +1 more source

Targeting aldehyde dehydrogenase for prostate cancer therapies

Frontiers in Oncology, 2022
Prostate cancer (PCa) is the most common cancer in men in the United States. About 10 – 20% of PCa progress to castration-resistant PCa (CRPC), which is accompanied by metastasis and therapeutic resistance.
Miao Ma, Wenyou He, Keyu Zhao, Linyuan Xue, Siyuan Xia, Baotong Zhang   +5 more
doaj   +1 more source

Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells [PDF]

, 2008
Conditioned medium (CM) from clonal sub-populations of the pancreatic cancer cell line, MiaPaCa-2 with differing invasive abilities, were examined for their effect on in vitro invasion.
Naomi Walsh, Martin Clynes, Clynes, Martin, O'Donovan, Norma, Michael Henry, Walsh, Naomi, Dowling, Paul, Paula Meleady, Meleady, Paula, Norma O'Donovan, O\u27Donovan, Norma, Henry, Michael, Paul Dowling   +12 more
core   +2 more sources

Development of a New Screen-Printed Transducer for the Electrochemical Detection of Thiram

Chemosensors, 2021
A new transducer based on a screen-printed carbon electrode has been developed for the quantification of thiram. Detection of this fungicide is based on the performance of two enzymes: (1) aldehyde dehydrogenase catalyzes the aldehyde oxidation using NAD+
David Ibáñez, Daniel Izquierdo-Bote, María Begoña González-García, David Hernández-Santos, Pablo Fanjul-Bolado   +4 more
doaj   +1 more source

ALDH2 mediates 5-nitrofuran activity in multiple species [PDF]

, 2012
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, but despite relative ...
Spitzer, Michaela, Brear, Paul, Patton, E. Elizabeth, Johnson, Stephen L, Patton, E Elizabeth, Zeng, Zhiqiang, Patton, Elizabeth, Mitchell, Amy, Ishizaki, Hironori, Taylor, Kerrie L, Johnson, Stephen L., Taylor, Kerrie L., Smith, Terry K., Westwood, Nicholas J, Patton, E Elizabeth; id_orcid, Marie, K.L.; id_orcid, McNeil, Ewan, Temperley, Nicholas, Tyers, Mike, Melton, David W, Zhou, Linna, Temperley, Nicholas D., Temperley, Nicholas D, Gautier, Philippe, Taylor, Kerrie, Narayan, Vikram, Melton, David, Westwood, Nicholas James, Melton, David W., Smith, Terry K, Johnson, Stephen, McNeil, Ewan M, McNeil, Ewan M., Westwood, Nicholas J.   +33 more
core   +1 more source

The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia

Haematologica, 2020
Leukemic stem cells are multipotent, self-renewing, highly proliferative cells that can withstand drug treatments. Although currently available treatments potentially destroy blast cells, they fail to eradicate leukemic progenitor cells completely ...
Charyguly Annageldiyev, Krishne Gowda, Trupti Patel, Priyanjali Bhattacharya, Su-Fern Tan, Soumya Iyer, Dhimant Desai, Sinisa Dovat, David J. Feith, Thomas P. Loughran, Shantu Amin, David Claxton, Arati Sharma   +12 more
doaj   +1 more source