Results 11 to 20 of about 329,736 (281)

Human Aldehyde Dehydrogenase E3 Isozyme Is a Betaine Aldehyde Dehydrogenase

Biochemical and Biophysical Research Communications, 1995
The E3 isozyme of human aldehyde dehydrogenase (EC 1.2.1.3), with broad substrate specificity, which also catalyzes dehydrogenation of 4-aminobutyraldehyde, was purified and sequenced recently (1,3). It has been shown during this investigation to have betaine aldehyde dehydrogenase activity.
M K, Chern, R, Pietruszko
openaire   +3 more sources

Aldehyde dehydrogenase in tobacco pollen [PDF]

Plant Molecular Biology, 1997
Acetaldehyde is one of the intermediate products of ethanolic fermentation, which can be reduced to ethanol by alcohol dehydrogenase (ADH). Alternatively, acetaldehyde can be oxidized to acetate by aldehyde dehydrogenase (ALDH) and subsequently converted to acetyl-CoA by acetyl-CoA synthetase (ACS).
op den Camp RG, Kuhlemeier C
openaire   +6 more sources

The diagnostic value of alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) measurement in the sera of patients with brain tumor

Archives of Medical Science, 2017
Introduction: Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) exist in the brain. Alcohol dehydrogenase and ALDH are also present in brain tumor cells.
Wojciech Jelski, Magdalena Laniewska-Dunaj, Karolina Orywal, Jan Kochanowicz, Robert Rutkowski, Maciej Szmitkowski   +5 more
doaj   +2 more sources

Supplementary Figure from Plasticity within Aldehyde Dehydrogenase–Positive Cells Determines Prostate Cancer Radiosensitivity

, 2022
Supplementary Figure from Plasticity within Aldehyde Dehydrogenase–Positive Cells Determines Prostate Cancer ...
Anja Voss-Böhme (15098793), Annett Linge (15009665), Iñaki Schniewind (15098772), Antje Dietrich (15098790), Anna Dubrovska (105746), Daria Klusa (15098787), Steffen Lange (15098778), Mechthild Krause (15009659), Steffen Löck (15098784), Shivaprasad G. Patil (15098781), Ina Kurth (15098796), Claudia Peitzsch (7817477), Franziska M. Schwarz (15098769), Maria J. Besso (15098775), Ali Nowrouzi (200898)   +14 more
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Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans.

PLoS Genetics, 2021
The intracellular level of fatty aldehydes is tightly regulated by aldehyde dehydrogenases to minimize the formation of toxic lipid and protein adducts. Importantly, the dysregulation of aldehyde dehydrogenases has been implicated in neurologic disorder ...
Lidan Zeng, Xuesong Li, Christopher B Preusch, Gary J He, Ningyi Xu, Tom H Cheung, Jianan Qu, Ho Yi Mak   +7 more
doaj   +1 more source

Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal

Journal of Lipid Research, 2010
Fatty aldehyde dehydrogenase (EC 1.2.1.48) converts long-chain fatty aldehydes to the corresponding acids. Deficiency in this enzyme causes the Sjogren Larsson Syndrome, a rare inherited disorder characterized by ichthyosis, spasticity, and mental ...
Markus A. Keller, Katrin Watschinger, Georg Golderer, Manuel Maglione, Bettina Sarg, Herbert H. Lindner, Gabriele Werner-Felmayer, Alessandro Terrinoni, Ronald J.A. Wanders, Ernst R. Werner   +9 more
doaj   +1 more source

Unsupervised Learning for Feature Representation Using Spatial Distribution of Amino Acids in Aldehyde Dehydrogenase (ALDH2) Protein Sequences

Mathematics, 2022
Aldehyde dehydrogenase 2 (ALDH2) enzyme is required for alcohol detoxification. ALDH2 belongs to the aldehyde dehydrogenase family, the most important oxidative pathway of alcohol digestion. Two main liver isoforms of aldehyde dehydrogenase are cytosolic
Monika Khandelwal, Sabha Sheikh, Ranjeet Kumar Rout, Saiyed Umer, Saurav Mallik, Zhongming Zhao   +5 more
doaj   +1 more source

Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells [PDF]

, 2008
Conditioned medium (CM) from clonal sub-populations of the pancreatic cancer cell line, MiaPaCa-2 with differing invasive abilities, were examined for their effect on in vitro invasion.
Naomi Walsh, Martin Clynes, Clynes, Martin, O'Donovan, Norma, Michael Henry, Walsh, Naomi, Dowling, Paul, Paula Meleady, Meleady, Paula, Norma O'Donovan, O\u27Donovan, Norma, Henry, Michael, Paul Dowling   +12 more
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ALDH2 mediates 5-nitrofuran activity in multiple species [PDF]

, 2012
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, but despite relative ...
Spitzer, Michaela, Brear, Paul, Johnson, Stephen L, Patton, E Elizabeth, Zeng, Zhiqiang, Patton, Elizabeth, Mitchell, Amy, Ishizaki, Hironori, Taylor, Kerrie L, Smith, Terry K., Westwood, Nicholas J, Patton, E Elizabeth; id_orcid, Marie, K.L.; id_orcid, McNeil, Ewan, Temperley, Nicholas, Tyers, Mike, Melton, David W, Zhou, Linna, Temperley, Nicholas D, Gautier, Philippe, Taylor, Kerrie, Narayan, Vikram, Melton, David, Westwood, Nicholas James, Smith, Terry K, Johnson, Stephen, McNeil, Ewan M, Westwood, Nicholas James; id_orcid, Smith, Terry K; id_orcid, McNeil, Ewan M., Johnson, Stephen L., Temperley, Nicholas D., Patton, E. Elizabeth, Melton, David W., Westwood, Nicholas J.   +34 more
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Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport [PDF]

, 2011
A compartmental model for the in vitro uptake kinetics of the anti-cancer agent topotecan (TPT) has been extended from a previously published model. The extended model describes the drug activity and delivery of the pharmacologically active form to the ...
N.D. Evans, Evans, Neil D., M.J. Chappell, Errington, Rachel J., R.J. Errington, Smith, Paul J., Smith, Paul James, Atari, M. I., Chappell, M. J., P.J. Smith, Chappell, M. J. (Michael J.), M.I. Atari, Errington, Rachel Jane, Evans, N. D.   +13 more
core   +1 more source