Results 41 to 50 of about 262,052 (188)

11-Hydroxythromboxane B2 dehydrogenase is identical to cytosolic aldehyde dehydrogenase [PDF]

open access: yes, 1994
11 -Hydroxythromboxane B2 dehydrogenase purified from porcine kidney has been identified as cytosolic aldehyde dehydrogenase (EC 1.2.1.3). This identification is based on protein characteristics, sequence analysis of one proteolytic digest, blocked N ...
Jörnvall, Hans   +11 more
core   +1 more source

Taxonomic distribution of alkane synthesizing aldehyde dehydrogenases across bacteria, fungi, plants, and animals

open access: yesBiotechnology for Biofuels and Bioproducts
Background Hydrocarbon-based biofuels, known as drop-in fuels, which are chemically similar to petroleum, have gained significant attention. Microorganisms that produce medium-chain alkanes hold promise for the bioproduction of drop-in fuels.
Masakazu Ito   +6 more
doaj   +1 more source

Aldehyde Dehydrogenase Enzyme Functions in Acute Leukemia Stem Cells

open access: yesFrontiers in Bioscience-Scholar, 2022
The enzymes that belong to the aldehyde dehydrogenase family are expressed in a variety of cells; yet activity of their main members characterizes stem cells, both normal and malignant.
Garrett M. Dancik   +2 more
doaj   +1 more source

Nitric oxide (II) as a modulator of aldehyde dehydrogenase activity in human erythrocytes [PDF]

open access: yesJournal of Stress Physiology & Biochemistry
The aim of this work is estimation of effects and its mechanisms of gaseous nitric oxide and dinitrosyl iron complexes (DNIC) on catalytic activity of aldehyde dehydrogenase.
Andrew K. Martusevich   +4 more
doaj  

Coupled regulations of enzymatic activity and structure formation of aldehyde dehydrogenase Ald4p

open access: yesBiology Open, 2020
Previously, we have developed an extramitochondrial assembly system, where mitochondrial targeting signal (MTS) can be removed from a given mitochondrial enzyme, which could be used to characterize the regulatory factors involved in enzyme assembly ...
Chalongrat Noree   +1 more
doaj   +1 more source

Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer

open access: yesClinics, 2013
OBJECTIVE: To analyze the expression of hypoxia-inducible factors (hypoxia-inducible factor 1A and hypoxia-inducible factor 2A) and aldehyde dehydrogenase proteins in patients with locally advanced breast carcinoma who were subjected to neoadjuvant ...
Daniel Guimarães Tiezzi   +6 more
doaj  

Update on the aldehyde dehydrogenase gene (ALDH) superfamily

open access: yesHuman Genomics, 2011
Members of the aldehyde dehydrogenase gene (ALDH) superfamily play an important role in the enzymic detoxification of endogenous and exogenous aldehydes and in the formation of molecules that are important in cellular processes, like retinoic acid ...
Jackson Brian   +6 more
doaj   +1 more source

Single amino acid exchanges affect the substrate preference of an acetaldehyde dehydrogenase

open access: yesApplied Microbiology and Biotechnology
The NAD+-dependent aldehyde dehydrogenase AldB from Aromatoleum aromaticum was recombinantly produced in Escherichia coli and biochemically characterized.
Dominik Hege   +5 more
doaj   +1 more source

Aldehyde dehydrogenases and cell proliferation [PDF]

open access: yesFree Radical Biology and Medicine, 2012
Aldehyde dehydrogenases (ALDHs) oxidize aldehydes to the corresponding carboxylic acids using either NAD or NADP as a coenzyme. Aldehydes are highly reactive aliphatic or aromatic molecules that play an important role in numerous physiological, pathological, and pharmacological processes.
G, Muzio   +4 more
openaire   +2 more sources

Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning

open access: yesCell Reports, 2019
Summary: Parkinson’s disease causes the most profound loss of the aldehyde dehydrogenase 1A1-positive (ALDH1A1+) nigrostriatal dopaminergic neuron (nDAN) subpopulation.
Junbing Wu   +20 more
doaj   +1 more source

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