Results 31 to 40 of about 329,736 (281)

Aldehyde dehydrogenase 2 and arrhythmogenesis

open access: yesHeart Rhythm, 2022
Cardiac arrhythmia is a common cardiovascular disease that leads to considerable economic burdens and significant global public health challenges. Despite the remarkable progress made in recent decades, antiarrhythmic therapy remains suboptimal. Aldehyde dehydrogenase 2 (ALDH2), a critical detoxifying enzyme, catalyzes toxic aldehydes and protects ...
Junyan, Jin, Jieying, Chen, Yaping, Wang
openaire   +2 more sources

Functional characterization of SlscADH1, a fruit-ripening associated short-chain alcohol dehydrogenase of tomato [PDF]

open access: yes, 2012
A tomato short-chain dehydrogenase-reductase (SlscADH1) is preferentially expressed in fruit with a maximum expression at the breaker stage while expression in roots, stems, leaves and flowers is very weak.
Moummou, Hanane   +8 more
core   +1 more source

SAXS fingerprints of aldehyde dehydrogenase oligomers

open access: yesData in Brief, 2015
Enzymes of the aldehyde dehydrogenase (ALDH) superfamily catalyze the nicotinamide adenine dinucleotide-dependent oxidation of aldehydes to carboxylic acids.
John J. Tanner
doaj   +1 more source

Influence of food commodities on hangover based on alcohol dehydrogenase and aldehyde dehydrogenase activities

open access: yesCurrent Research in Food Science, 2019
Alcohol consumption often leads to hangover, a condition characterized by several symptoms, characteristically headache, nausea, fatigue and drowsiness. Hangover may be alleviated by altering the rate of alcohol metabolism and facilitating elimination of
Shraddha Srinivasan   +2 more
doaj   +1 more source

Development of a New Screen-Printed Transducer for the Electrochemical Detection of Thiram

open access: yesChemosensors, 2021
A new transducer based on a screen-printed carbon electrode has been developed for the quantification of thiram. Detection of this fungicide is based on the performance of two enzymes: (1) aldehyde dehydrogenase catalyzes the aldehyde oxidation using NAD+
David Ibáñez   +4 more
doaj   +1 more source

Direct electron transfer-type bioelectrocatalysis by membrane-bound aldehyde dehydrogenase from Gluconobacter oxydans and cyanide effects on its bioelectrocatalytic properties

open access: yesElectrochemistry Communications, 2021
The bioelectrocatalytic properties of membrane-bound aldehyde dehydrogenase (AlDH) from Gluconobacter oxydans NBRC12528 were evaluated. AlDH exhibited direct electron transfer (DET)-type bioelectrocatalytic activity for acetaldehyde oxidation at several ...
Taiki Adachi   +3 more
doaj   +1 more source

A Prodrug Strategy for the In Vivo Imaging of Aldehyde Dehydrogenase Activity [PDF]

open access: yes, 2022
Therapy resistance is one of the biggest challenges facing clinical oncology. Despite a revolution in new anti-cancer drugs targeting multiple components of the tumour microenvironment, acquired or innate resistance frequently blunts the efficacy of ...
Raul , Pereira   +5 more
core   +1 more source

Characterization of mouse mitochondrial aldehyde dehydrogenase.

open access: yes, 1994
Characterization of mouse mitochondrial aldehyde ...
John Lawrence. Baloy (7951076)
core   +2 more sources

Aldehyde Dehydrogenase and Aldo-Keto Reductase Enzymes: Basic Concepts and Emerging Roles in Diabetic Retinopathy

open access: yesAntioxidants, 2023
Diabetic retinopathy (DR) is a complication of diabetes mellitus that can lead to vision loss and blindness. It is driven by various biochemical processes and molecular mechanisms, including lipid peroxidation and disrupted aldehyde metabolism, which ...
Burak Mugdat Karan   +4 more
doaj   +1 more source

The Role of Pesticide-Induced Aldehyde Dehydrogenase Inhibition in the Pathogenesis of Parkinson’s Disease [PDF]

open access: yes, 2012
Parkinson’s disease (PD) is a neurodegenerative disorder particularly characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. Its etiology is unknown but likely includes both genetic and environmental factors.
Fitzmaurice, Arthur Gerald, III
core   +1 more source

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