Results 51 to 60 of about 262,052 (188)

Circulating Pro-Vascular Progenitor Cell Depletion During Type 2 Diabetes

open access: yesJACC: Basic to Translational Science, 2019
Summary: Detection of vascular regenerative cell exhaustion is required to combat ischemic complications during type 2 diabetes mellitus (T2D). We used high aldehyde dehydrogenase (ALDH) activity and surface marker co-expression to develop a high ...
Daniella C. Terenzi, BHSc   +5 more
doaj   +1 more source

Cyanamide Potentiates the Ethanol-Induced Impairment of Receptor-Mediated Endocytosis in a Recombinant Hepatic Cell Line Expressing Alcohol Dehydrogenase Activity

open access: yesInternational Journal of Hepatology, 2012
Ethanol administration has been shown to alter receptor-mediated endocytosis in the liver. We have developed a recombinant hepatic cell line stably transfected with murine alcohol dehydrogenase cDNA to serve as an in vitro model to investigate these ...
Dahn L. Clemens   +2 more
doaj   +1 more source

Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition

open access: yesiScience
Summary: IL-17-producing helper T (Th17) cells are long-lived and serve as central effector cells in chronic autoimmune diseases. The underlying mechanisms of Th17 persistence remain unclear. We demonstrated that abatacept, a CD28 antagonist, effectively
By Yukiko Tokifuji   +8 more
doaj   +1 more source

Evidence for mitochondrial localization of betaine aldehyde dehydrogenase in rat liver - purification, characterization and comparison with human cytoplasmic E3 isozyme

open access: yes, 2013
Betaine aldehyde dehydrogenase has been purified to homogeneity from rat liver mitochondria. The properties of betaine aldehyde dehydrogenase were similar to those of human cytoplasmic E3 isozyme in substrate specificity and kinetic constants for ...
Pietruszko, Regina   +1 more
core  

Cloning, heterologous expression, purification, and kinetic analysis of aldehyde dehydrogenase 4 of Saccharomyces cerevisiae.

open access: yes, 2010
碩士酵母菌醛類去氫酶4(YOR374w)是一種位在粒線體內的去氫酶,需要鉀離子的活化,以及NAD+或NADP+當輔酶,在乙醇的代謝途徑扮演很重要的角色,尤其是以乙醇當碳源的環境下。為了了解醛類去氫酶對於其他不同代謝途徑是否有影響,經由選殖出正確ALD4基因,再利用大腸桿菌大量的表現出ald4p,透過管柱層析純化之後,對許多不同的受質做活性分析。在酵母菌的泛酸生合成途徑中,3-aminopropanal氧化成beta-alanine是重要的一個反應,而glycine betaine是一種滲透壓保護劑 ...
陳俊傑; Chen, Jyun-jie
core   +1 more source

Cell culture models and novel gene therapeutic strategies for colorectal cancer [PDF]

open access: yes, 2006
The development of relevant cellular model systems for colorectal cancer is of utmost importance for an improved in vitro assessment of therapeutic strategies against colorectal cancer. Recently published low passage colon cancer cell lines that closely
Gaedtke, Lars
core   +1 more source

Influence of food commodities on hangover based on alcohol dehydrogenase and aldehyde dehydrogenase activities

open access: yesCurrent Research in Food Science, 2019
Alcohol consumption often leads to hangover, a condition characterized by several symptoms, characteristically headache, nausea, fatigue and drowsiness. Hangover may be alleviated by altering the rate of alcohol metabolism and facilitating elimination of
Shraddha Srinivasan   +2 more
doaj   +1 more source

Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma

open access: yesTumor Biology, 2017
Tumor necrosis factor receptor–associated factor 1, an adaptor protein of tumor necrosis factor 2, is involved in classical nuclear factor (NF)-κB activation and lymphocyte recruitment. However, less is known about the expression and association of tumor
Tian-Fu Wu   +5 more
doaj   +1 more source

Biochemical changes of lipids in plant foods and feeds. II. Lipid hydroperoxides metabolism

open access: yesGrasas y Aceites, 1991
The enzymes of the lipoxygenase pathway in plant foods are reviewed. This part analyzes the enzymes related to the descomposition or transformation of the lipidic hydroperoxides.
R. Zamora, F. J. Hidalgo, M. Alaiz
doaj   +1 more source

ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial)) [PDF]

open access: yes, 2002
Review on ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial)), with data on DNA, on the protein encoded, and where the gene is ...
Sophos, N, Vasiliou, V
core   +1 more source

Home - About - Disclaimer - Privacy