Integrating Horizontal Gene Transfer and Common Descent to Depict Evolution and Contrast It with ‘‘Common Design [PDF]
, 2010 Horizontal gene transfer (HGT) and common descent interact in space and time. Because events of HGT co-occur with phylogenetic evolution, it is difficult to depict evolutionary patterns graphically. Tree-like representations of life’s diversification are
Espinosa, Avelina +1 more
core +2 more sources
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Gene Therapy Correction of Aldehyde Dehydrogenase 2 Deficiency
Molecular Therapy: Methods & Clinical Development, 2019 Aldehyde dehydrogenase 2 (ALDH2) deficiency causes “Asian flush syndrome,” presenting as alcohol-induced facial flushing, tachycardia, nausea, and headaches.
Yuki Matsumura +6 more
doaj +1 more source
Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells [PDF]
, 2016 Aldehyde dehydrogenases participate in a variety of cellular homeostatic mechanisms like metabolism, proliferation, differentiation, apoptosis, whereas recently, they have been implicated in normal and cancer cell stemness.
Chlichlia, Katerina +8 more
core +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Aldehyde Dehydrogenase Enzyme Functions in Acute Leukemia Stem Cells
Frontiers in Bioscience-Scholar, 2022 The enzymes that belong to the aldehyde dehydrogenase family are expressed in a variety of cells; yet activity of their main members characterizes stem cells, both normal and malignant.
Garrett M. Dancik +2 more
doaj +1 more source
Aldehyde Dehidrogenase Level and Fatty Acid Ethyl Ester as Biochemical Markers Persist Longer Than Ethanol in Wistar Rats After Chronic Alcohol Consumption [PDF]
, 2010 Alcohol consumption in human has increased from year to year in Indonesia and more recently, anincreasing number of cases of alcohol intoxication, alcoholic liver disease, and death were observed.The purpose of this experimental study was to examine the ...
Astawa, N. M. (Nyoman) +3 more
core
Comparative genomics and mutagenesis analyses of choline metabolism in the marine Roseobacter clade [PDF]
, 2015 Choline is ubiquitous in marine eukaryotes and appears to be widely distributed in surface marine waters; however, its metabolism by marine bacteria is poorly understood.
Andresen P.A. +6 more
core +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Biotechnology for Biofuels and BioproductsBackground Hydrocarbon-based biofuels, known as drop-in fuels, which are chemically similar to petroleum, have gained significant attention. Microorganisms that produce medium-chain alkanes hold promise for the bioproduction of drop-in fuels.
Masakazu Ito +6 more
doaj +1 more source