Results 51 to 60 of about 329,736 (281)

Electron Donor–Acceptor Complex Catalysis in Synthetic Chemistry

Angewandte Chemie, EarlyView.
Electron donor–acceptor (EDA) complexes are moving beyond stoichiometric photoactivation toward catalytic platforms for radical generation. Productive EDA catalysis requires coordinated donor–acceptor association, charge‐transfer excitation, radical reactivity, and vcatalyst turnover.
Tristan von Münchow, Andrea Palone, Jonathan Samuel Trimble, Paolo Melchiorre   +3 more
wiley   +2 more sources

Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity

Nature Communications, 2019
Aldehyde-alcohol dehydrogenase (AdhE) converts acetyl-CoA to ethanol and plays an important role in bacterial fermentation. Here the authors present the 3.5 Å cryo-EM structure of full-length E.
Gijeong Kim, Liyana Azmi, Seongmin Jang, Taeyang Jung, Hans Hebert, Andrew J. Roe, Olwyn Byron, Ji-Joon Song   +7 more
doaj   +1 more source

Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning

Cell Reports, 2019
Summary: Parkinson’s disease causes the most profound loss of the aldehyde dehydrogenase 1A1-positive (ALDH1A1+) nigrostriatal dopaminergic neuron (nDAN) subpopulation.
Junbing Wu, Justin Kung, Jie Dong, Lisa Chang, Chengsong Xie, Ahsan Habib, Sarah Hawes, Nannan Yang, Vivian Chen, Zhenhua Liu, Rebekah Evans, Bo Liang, Lixin Sun, Jinhui Ding, Jia Yu, Sara Saez-Atienzar, Beisha Tang, Zayd Khaliq, Da-Ting Lin, Weidong Le, Huaibin Cai   +20 more
doaj   +1 more source

Insights into Aldehyde Dehydrogenase Enzymes: A Structural Perspective

Frontiers in Molecular Biosciences, 2021
Aldehyde dehydrogenases engage in many cellular functions, however their dysfunction resulting in accumulation of their substrates can be cytotoxic. ALDHs are responsible for the NAD(P)-dependent oxidation of aldehydes to carboxylic acids, participating ...
Kim Shortall, Ahmed Djeghader, Edmond Magner, Tewfik Soulimane   +3 more
doaj   +1 more source

Aldehyde dehydrogenase (ALDH) protein families in Brachypodium distachyon.

, 2016
Aldehyde dehydrogenase (ALDH) protein families in Brachypodium distachyon.
Tagnon D. Missihoun (3307968), Dorothea Bartels (2572201), Simeon O. Kotchoni (234212)   +2 more
core   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Nitric oxide (II) as a modulator of aldehyde dehydrogenase activity in human erythrocytes [PDF]

Journal of Stress Physiology & Biochemistry
The aim of this work is estimation of effects and its mechanisms of gaseous nitric oxide and dinitrosyl iron complexes (DNIC) on catalytic activity of aldehyde dehydrogenase.
Andrew K. Martusevich, Anna G. Soloveva, Vladimir V. Kononets, Alexander V. Kuptsov, Mikhail A. Zarembovsky   +4 more
doaj  

The Aldehyde Dehydrogenase Gene Superfamily Resource Center

Human Genomics, 2009
The website http://www.aldh.org is a publicly available database for nomenclature and functional and molecular sequence information for members of the aldehyde dehydrogenase (ALDH) gene superfamily for animals, plants, fungi and bacteria.
Black William, Vasiliou Vasilis
doaj   +1 more source

Aldehyde dehydrogenases and cell proliferation [PDF]

Free Radical Biology and Medicine, 2012
Aldehyde dehydrogenases (ALDHs) oxidize aldehydes to the corresponding carboxylic acids using either NAD or NADP as a coenzyme. Aldehydes are highly reactive aliphatic or aromatic molecules that play an important role in numerous physiological, pathological, and pharmacological processes.
G, Muzio, M, Maggiora, E, Paiuzzi, M, Oraldi, R A, Canuto   +4 more
openaire   +2 more sources

Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis

Advanced Science, EarlyView.
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko, Eric S. Larsen, Govind Paneru, Kisung Lee, Diana V. Kolygina, Yankai Jia, Elizabeth Maria Clarissa, Wai‐Shing Wong, Bartosz A. Grzybowski   +8 more
wiley   +1 more source