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Discovery of a reversible ALDH1A3 inhibitor throwugh a consensus docking-based virtual screening study. [PDF]

open access: yesJ Comput Aided Mol Des
Batlle E   +5 more
europepmc   +1 more source

EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1

Experimental Cell Research, 2021
Aldehyde dehydrogenase 7 family member A1 (ALDH7A1) is an enzyme catalyzing lipid peroxidation of fatty aldehydes. It plays a critical role in sustaining high oxygen consumption rate (OCR) and ATP production in pancreatic ductal adenocarcinoma (PADC).
Jun Meng
exaly   +3 more sources

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