Results 71 to 80 of about 16,654 (227)

Computational Analysis of ZINC Analogues for Antidiabetic Phytochemical with Inhibitory Activity against Aldose Reductase Enzyme

, 2023
Filex Otieno, Samuel Munene, Cynthia Kyalo, Richard Kagia, Titus Suge   +4 more
openalex   +2 more sources

Hyperglycemia Impairs Acetylcholine-Induced Vasodilation of Retinal Arterioles Through Polyol Pathway–Independent Mechanisms in Rats

Journal of Pharmacological Sciences, 2010
We previously reported that acetylcholine (ACh)–induced vasodilation of retinal arterioles is diminished in diabetic rats; however, the underlying mechanism(s) of this phenomenon has not been fully elucidated.
Asami Mori, Orie Saigo, Kenji Sakamoto, Tsutomu Nakahara, Kunio Ishii   +4 more
doaj   +1 more source

Design and development of novel thiazole-sulfonamide derivatives as a protective agent against diabetic cataract in Wistar rats via inhibition of aldose reductase

, 2021
Liang Yin, Mingxue Zhang, Tiangeng He
openalex   +1 more source

Inhibitory Effects of Colocasia esculenta (L.) Schott Constituents on Aldose Reductase

Molecules, 2014
The goal of this study was to determine the rat lens aldose reductase-inhibitory effects of 95% ethanol extracts from the leaves of C. esculenta and, its organic solvent soluble fractions, including the dichloromethane (CH2Cl2), ethyl acetate (EtOAc), n-
Hong Mei Li, Seung Hwan Hwang, Beom Goo Kang, Jae Seung Hong, Soon Sung Lim   +4 more
doaj   +1 more source

Aldose Reductase Inhibition, Molecular Docking, and Density Functional Theory Studies of Dinaphthodiospyrol H from Diospyros kaki (Japanese Persimmon)

Journal of Pure and Applied Microbiology
This study explores the aldose reductase (AR) inhibitory potential of dinaphthodiospyrol H, a compound isolated from Diospyros kaki (Japanese persimmon).
Abdur Rauf, Saima Naz, Zubair Ahmad, Umer Rashid, Marryum, Khurshid Ayub, Muhammad Aetizaz, Ho Soonmin, Naveed Muhammad, Mujeeb-ur-Rehman, Walaa F. Alsanie, Abdulhakeem S. Alamri   +11 more
doaj   +1 more source

The use of dimethylsulfoxide as a solvent in enzyme inhibition studies: the case of aldose reductase

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
Aldose reductase (AR) is an enzyme devoted to cell detoxification and at the same time is strongly involved in the aetiology of secondary diabetic complications and the amplification of inflammatory phenomena.
Livia Misuri, Mario Cappiello, Francesco Balestri, Roberta Moschini, Vito Barracco, Umberto Mura, Antonella Del-Corso   +6 more
doaj   +1 more source

Benzothiazole Analogues: As Aldose Reductase Inhibitor (ARIs) for the Management of Diabetic Neuropathy and Cardiomyopathy

, 2023
Rima Mahapatra Kuntal Hazra
openalex   +1 more source

Oxidation of aldoses with bromine

Journal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1962
Rates of oxidation of aldoses with bromine have been reappraised and interpreted in the light of present concepts of conformation and reaction mechanism. It is suggested that differences in the rates of oxidation of the α and β anomers are largely determined by differences in the free energy required by the reactants for passing from the ground state ...
openaire   +1 more source

Study on Aldose Reductase Inhibitors Based on Quinoxalin Structure [PDF]

, 2018
Yang Li, Bing Ma
openalex   +1 more source

Influence of minerals on aldose formation during hydrothermal processes in meteorite parent bodies

Progress in Earth and Planetary Science
Various prebiotic organic compounds have been identified in meteorites. Understanding the origins of these compounds is essential to comprehending prebiotic chemistry in the early Solar System.
Taiyu Fujii, Shunpei Abe, Naoki Hirakawa, Kensei Kobayashi, Yoko Kebukawa   +4 more
doaj   +1 more source