Results 21 to 30 of about 14,544 (270)
Tonicity response element binding protein associated with neuronal cell death in the experimental diabetic retinopathy [PDF]
, 2014 AIM: To study the contribution of tonicity response element binding protein (TonEBP) in retinal ganglion cell (RGC) death of diabetic retinopathy (DR). METHODS: Diabetes was induced in C57BL/6 mice by five consecutive intraperitoneal injections of 55 mg/
Choi, Wan-Sung +6 more
core +2 more sources
Molecules, 2007 During the course of studies directed towards the discovery of novel aldose reductase inhibitors for the treatment of diabetic complications, we synthesized a series of new (Z)-3-phenyl-2-benzoylpropenoic acid derivatives and tested their in vitro ...
Shao-Jie Wang +4 more
doaj +1 more source
JACC: Case Reports, 2020 We describes a case of a critically ill patient with myocarditis and severe acute respiratory distress syndrome related to coronavirus disease-2019.
Justin Coyle, DO +5 more
doaj +1 more source
Tikrit Journal of Pure Science, 2023 This work includes a new spectrophotometric method for the determination para aminosalicylic acid in aqueous medium based on the oxidation by NaIO4 and coupling with 4-Amino Antipyrine producing a red dye soluble in water and of גmax of 516 nm.
Asma'a H. Shakir
doaj +1 more source
A recipe for myositis : nuclear factor κB and nuclear factor of activated T-cells transcription factor pathways spiced up by cytokines [PDF]
, 2017 Nuclear factor κB (NF-κB) is a well-known pro-inflammatory transcription factor that regulates the expression of the tissue’s immune-active components, which include cytokines, chemokines and adhesion molecules.
De Paepe, Boel
core +3 more sources
Marine Drugs, 2021 An in-depth study on the inhibitory mechanism on protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AR) enzymes, including analysis of the insulin signalling pathway, of phosphoeleganin, a marine-derived phosphorylated polyketide, was achieved.
Massimo Genovese +8 more
doaj +1 more source
Relationship between Aldose reductase and superoxide dismutase inhibition capacities of indole-based analogs of melatonin derivatives [PDF]
, 2009 Aldose reductase (AR) has been implicated in the etiology of diabetic complications. Under diabetic conditions, the elevated vascular glucose level causes an increased flux through the polyol pathway, which induces functional and morphological changes ...
Daş-Evcimen N., Suzen S., Yildirim Ö.
core +1 more source
Bangladesh Journal of Pharmacology, 2012 The primary objective of this study was to investigate the aldose reductase inhibitory activity of flavonoids using in silico docking studies. In this perspective, flavonoids like biochanin, butein, esculatin, fisetin and herbacetin were selected ...
Arumugam Madeswaran +5 more
doaj +1 more source
Evaluation of Efficacy and Safety of Epalrestat (150 mg) Compared to Epalrestat (50 mg) in Patients Suffering from Diabetic Peripheral Neuropathy [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Epalrestat is currently the only Aldose Reductase Inhibitor (ARI) approved to treat symptoms of Diabetic Peripheral Neuropathy (DPN).
Sachin Devendrarao Shende +2 more
doaj +1 more source
Defatted Seeds of Oenothera biennis as a Potential Functional Food Ingredient for Diabetes
Foods, 2021 The defatted seeds of Oenothera biennis (DSOB) are a by-product of evening primrose oil production that are currently not effectively used. In this study, α-glucosidase inhibition, aldose reductase inhibition, antioxidant capacity, polyphenol composition,
Zhiqiang Wang +4 more
doaj +1 more source