Metabolic Requirements for Active Sodium Transport Stimulated by Aldosterone
Geoffrey W.G. Sharp, Alexander Leaf
openalex +1 more source
Abstract Structured medication reviews (SMRs) were introduced into the National Health Service (NHS) Primary Care to support the delivery of the NHS Long‐Term Plan for medicines optimization. SMRs improve the quality of care, reduce harm and offer value for money. However, evidence to support SMRs for patients with chronic kidney disease (CKD) stage G4‐
Cathy Margaret Pogson+3 more
wiley +1 more source
C-terminal FGF-23 production coupling with aldosterone via FAM20C and predicting cardiovascular events in primary aldosteronism. [PDF]
Wu VC+8 more
europepmc +1 more source
Advancing antihypertensive drug development
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu+5 more
wiley +1 more source
Association of plasma aldosterone concentration with peripheral artery disease in hypertensive patients: insights from a large cross-sectional analysis. [PDF]
Zhang Y+13 more
europepmc +1 more source
Prevalence of Metabolic‐Associated Steatotic Liver Disease in Patients With Primary Aldosteronism
ABSTRACT Objective To assess the prevalence of metabolic associated steatotic liver disease (MASLD) in patients with primary aldosteronism (PA) compared to benign adrenal adenomas, and to evaluate the impact of hormonal excess in inducing MASLD. Design Single‐centre retrospective study. Methods Hepatic steatosis was assessed by liver/spleen (L/S) ratio
Irene Tizianel+6 more
wiley +1 more source
A Rare Case of Primary Hyperaldosteronism Resulting in Severe Hypokalemia. [PDF]
Sameer S+4 more
europepmc +1 more source
Is It Possible to Screen for Primary Aldosteronism Effectively in Primary Care?
ABSTRACT Objective Primary aldosteronism (PA) is the commonest secondary cause of hypertension but case‐detection remains a challenge. Screening is usually performed in secondary care using an aldosterone:renin ratio (ARR) measurement. Here, we describe the outcomes of screening in primary care, in Oxfordshire, UK.
Harsha Anuruddhika Dissanayake+9 more
wiley +1 more source
The prognostic value of CXCR4 PET/CT imaging in unilateral primary aldosteronism patients after adrenalectomy. [PDF]
Shao S+9 more
europepmc +1 more source
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan+14 more
wiley +1 more source