Results 351 to 360 of about 230,682 (392)
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Canadian Journal of Biochemistry and Physiology, 1955
In 10 experiments, 50–98% of aldosterone added to urine could be recovered in the neutral fraction. Purification of the urinary extracts by various chromatographic procedures resulted in loss of activity. Following an intravenous administration of 600 μgm.
Eleanor H. Venning +3 more
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In 10 experiments, 50–98% of aldosterone added to urine could be recovered in the neutral fraction. Purification of the urinary extracts by various chromatographic procedures resulted in loss of activity. Following an intravenous administration of 600 μgm.
Eleanor H. Venning +3 more
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Suppression of Aldosterone by Cyproheptadine in Idiopathic Aldosteronism
New England Journal of Medicine, 1981To study the role of serotonin in regulating the release of aldosterone, we gave single, oral doses of cyproheptadine, an antiserotoninergic agent, to five normal volunteers with high aldosterone levels secondary to sodium deprivation and to 14 patients with aldosteronism (six with idiopathic aldosteronism due to bilateral adrenal hyperplasia and eight
Milton D. Gross +3 more
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Aldosterone and aldosterone antagonism in systemic hypertension
Current Hypertension Reports, 2004Aldosterone mediates both water and electrolyte balance by acting on the renal mineralocorticoid receptors. Recent experimental studies have also documented the presence of these receptors in other body organs, including the brain, blood vessels, and heart, suggesting that aldosterone plays a larger role in normal physiologic function and in ...
William H. Frishman, Charles T. Stier
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The regulation of aldosterone secretion in primary aldosteronism
The American Journal of Medicine, 1972Abstract Twenty patients with primary aldosteronism were studied under various conditions known to influence aldosterone secretion. All patients presented with the classic findings of hypertension, hypokalemia, suppressed plasma renin activity and nonsuppressible aldosterone secretion.
Gordon H. Williams +4 more
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Journal of Surgical Oncology, 2009
AbstractPrimary aldosteronism is the most common form of secondary hypertension. Case detection is based on an abnormal plasma aldosterone:plasma renin activity ratio and the diagnosis must be confirmed with an aldosterone suppression test. Subtype differentiation should be performed using adrenal venous sampling.
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AbstractPrimary aldosteronism is the most common form of secondary hypertension. Case detection is based on an abnormal plasma aldosterone:plasma renin activity ratio and the diagnosis must be confirmed with an aldosterone suppression test. Subtype differentiation should be performed using adrenal venous sampling.
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Trends in Cardiovascular Medicine, 2016
In 1955 Dr Jerome Conn first documented primary aldosteronism (PA). Since then, screening, diagnosis and treatment have developed, in the process both refining and complicating management. Currently, screening requires 4-6 weeks of lead-up, including major changes in antihypertensive therapy, followed by a blood draw for plasma aldosterone ...
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In 1955 Dr Jerome Conn first documented primary aldosteronism (PA). Since then, screening, diagnosis and treatment have developed, in the process both refining and complicating management. Currently, screening requires 4-6 weeks of lead-up, including major changes in antihypertensive therapy, followed by a blood draw for plasma aldosterone ...
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Aldosterone and the Kidney [PDF]
Hormone and Metabolic Research, 2011 The mineralocorticoid aldosterone is a key regulator of blood pressure, fluid and electrolyte homeostasis, and acts via the mineralocorticoid receptor (MR). In recent years, an increasing number of studies revealed deleterious effects of aldosterone via its receptor. Especially in patients with primary hyperaldosteronism (PHA) a significant higher risk
V. G. Fourkiotis +4 more
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Urologic Clinics of North America, 1988
Primary aldosteronism remains a diagnostic challenge. Despite the availability of sensitive and specific immunoassay techniques, the simplification of diagnostic testing, and the introduction of sensitive imaging techniques, there remain uncertainties about the optimal methods of screening, the sensitivity and specificity of various tests, diagnostic ...
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Primary aldosteronism remains a diagnostic challenge. Despite the availability of sensitive and specific immunoassay techniques, the simplification of diagnostic testing, and the introduction of sensitive imaging techniques, there remain uncertainties about the optimal methods of screening, the sensitivity and specificity of various tests, diagnostic ...
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Primary aldosteronism and aldosterone-associated hypertension
Journal of Clinical Pathology, 2008The field of primary aldosteronism (PA) and aldosterone-related hypertension has undergone rapid evolution. From a relatively rare curiosity PA has become a common problem particularly in selected hypertensive populations. Patients with PA and aldosterone-related hypertension appear to be at higher cardiovascular and renal risk than comparable patients
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