Results 1 to 10 of about 229,829 (311)
Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases
Frontiers in Endocrinology, 2023 The renin-angiotensin-aldosterone system (RAAS) is one of the key players in the regulation of blood volume and blood pressure. Dysfunction of this system is connected with cardiovascular and renal diseases.
Stepan Gambaryan +4 more
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Frontiers in Cardiovascular Medicine, 2023 Background and objectiveWhole body manipulation of the renin-angiotensin system (RAS) consistently exerts profound effects on experimental atherosclerosis development. A deficit in the literature has been a lack of attention to the effects of sex.
Masayoshi Kukida +19 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2023 Background: Renin-dependent hypertension with tubulointerstitial injury remains a problem with high prevalence in the clinic. However, whether and how renin participates in tubulointerstitial injury remains incompletely understood.
Chongjian Wang +8 more
doaj +1 more source
Assessing treatment adherence is crucial to determine adequacy of mineralocorticoid therapy
Endocrine Connections, 2023 Background: There is no consensus strategy for mineralocorticoid (MC) therapy titration in patients with primary adrenal insufficiency (PAI). W e aim to measure serum fludrocortisone (sFC) and urine fludrocortisone (uFC) levels and to determine their ...
Riccardo Pofi +6 more
doaj +1 more source
The Journal of Clinical Hypertension, 2022 This study aimed to evaluate the blood pressure (BP) lowing effect of low‐sodium (LS) salt substitution and how the effect influenced by plasma renin concentration (PRC) on middle‐aged and elderly hypertensive patients.
Li Che +5 more
doaj +1 more source
DIAGNOSIS OF ALDOSTEROMA. CLINICAL CASE
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020 A clinical case of hyperaldosteronism identifed during hospitalization in the endocrinology department of the Healthcare Institution «Grodno University Clinic» is presented.
Nikonova L. V. +3 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 PurposeThis study examined the effects of plasma renin activity (PRA), angiotensin II (Ang II) and aldosterone (PAC) concentrations as well as common polymorphisms in the β1-Adrenoceptor gene (ADRB1) and the G-protein α-Subunit (Gαs) protein gene the G ...
Weiwei Zeng +8 more
doaj +1 more source
Clinical Determinants and Prognostic Implications of Renin and Aldosterone in Patients with Symptomatic Heart Failure [PDF]
, 2020 Aims Activation of the renin-angiotensin-aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Anker, Stefan D. +17 more
core +5 more sources
Effect of amaranth proteins on the RAS system: In vitro, in vivo and ex vivo assays [PDF]
, 2020 The aim of this work was to analyse the hypotensive effect of amaranthprotein/peptides on spontaneously hypertensive rats (SHR). The mechanism of action of these peptides was studied in vivo and ex vivo.
Aphalo, Paula +4 more
core +2 more sources
Regulation of Renin Expression by Β1-Integrin in As4.1 Juxtaglomerular Line Cells
Biomedicines, 2023 (1) Background: Renal dysfunction and hypertension are mutually aggravating factors; however, the details of their interaction remain unclear. In a study using renal tissue from diabetic rats, we found that β1-integrin, a cell-substrate adhesion molecule,
Nobumichi Saito +7 more
doaj +1 more source