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Pharmacology of the renin-angiotensin system.

Folia Pharmacologica Japonica, 1994
Recent developments in the techniques of molecular biology and the availability of inhibitors of the renin-angiotensin system have provided new insight into renin-angiotensin research. The control mechanism of renin release and the metabolism of circulating renin have been well characterized on the molecular level. Angiotensin II has been shown to play
KIM, Shokei, YAMAMOTO, Kenjiro
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Local renin-angiotensin systems [PDF]

Molecular and Cellular Biochemistry, 1996
The existence of a local cardiovascular renin-angiotensin system (RAS) is often invoked to explain the long-term beneficial effects of RAS inhibitors in heart failure and hypertension. The implicit assumption is that all components of the RAS are synthesized in situ, so that local angiotensin II formation may occur independently of the circulating RAS.
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Manipulation of the Renin-Angiotensin System [PDF]

Circulation, 2001
Since the initial description of angiotensin II–mediated hypertension >40 years ago, basic and clinical investigations of the renin-angiotensin system (RAS) have resulted in a broader understanding of cardiovascular pathophysiology and significant advances in therapy.
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The renin angiotensin aldosterone system

Pflügers Archiv - European Journal of Physiology
AbstractIn this review, we will cover (i) the proteolytic cascade of the RAAS, (ii) its regulation by multiple feedback-controlled parameters, and (iii) the major effects of the RAAS. For the effects of the RAAS, we focus on the role of the RAAS in the regulation of volume homeostasis and vascular tone, as major determinants of arterial blood pressure.
Triebel, Hannah, Castrop, Hayo
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Renin-angiotensin system and atherosclerosis [PDF]