Results 21 to 30 of about 17,358,252 (203)

Renin-Angiotensin System [PDF]

open access: yesNew England Journal of Medicine, 1975
ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire   +3 more sources

The renin-angiotensin-aldosterone system during haemodialysis with acetate or bicarbonate at different dialysate sodium concentrations [PDF]

open access: yes, 1987
The hormones of the renin angiotensin aldosterone system were measured during regular haemodialysis with acetate or bicarbonate at dialysate sodium concentrations of 135, 140, 145, and 150 mmol/l.
Ress, K. M.   +3 more
core   +1 more source

ACE2 in the renin–angiotensin system

open access: yesClinical Science, 2020
AbstractIn 2020 we are celebrating the 20th anniversary of the angiotensin-converting enzyme 2 (ACE2) discovery. This event was a landmark that shaped the way that we see the renin–angiotensin system (RAS) today. ACE2 is an important molecular hub that connects the RAS classical arm, formed mainly by the octapeptide angiotensin II (Ang II) and its ...
Verano-Braga, Thiago   +4 more
openaire   +2 more sources

Furosemide stimulates renin expression in the kidneys of salt-supplemented rats [PDF]

open access: yes, 1993
This study was conducted to obtain information about a possible influence of salt transport by the thick ascending limb of Henle (TALH) and the macula densa on the expression of renin in the kidney.
Eckardt, K. U.   +6 more
core   +1 more source

Stimulation of renin secretion by potassium-channel activation with cromakalim [PDF]

open access: yes, 1989
The cardiovascular and endocrine profile of cromakalim has been studied in 8 healthy men (age 25 +/- 2 years: means SEM) and its influence on renin release from cultured rat juxtaglomerular cells in vitro has also been examined.
Kurtz, Armin   +6 more
core   +1 more source

The Frail Renin-Angiotensin System [PDF]

open access: yesClinics in Geriatric Medicine, 2011
Over the last few decades, the understanding of the renin-angiotensin system (RAS) has advanced dramatically. RAS is now thought to play a crucial role in physiologic and pathophysiologic mechanisms in almost every organ system and is a key regulator of hypertension, cardiovascular disease, and renal function.
openaire   +2 more sources

Calmodulin antagonists stimulate renin secretion and inhibit renin synthesis in vitro [PDF]

open access: yes, 1992
To find out whether calmodulin activity could be a common denominator for the cellular control of renin secretion and synthesis, we have examined the effects of calmodulin antagonists on the secretion and the synthesis of renin in primary cultures of ...
Kurtz, Armin   +7 more
core   +1 more source

Direct pro-inflammatory effects of prorenin on microglia.

open access: yesPLoS ONE, 2014
Neuroinflammation has been implicated in hypertension, and microglia have been proposed to play an important role in the progression of this disease. Here, we have studied whether microglia are activated within cardiovascular regulatory area(s) of the ...
Peng Shi   +8 more
doaj   +1 more source

The evolutionary development of the renin angiotensin aldosterone system and its importance for the survival of the human species

open access: yesArterial Hypertension, 2021
Kidneys produce a number of substances that affect intrarenal blood circulation; however, the key system that regulates blood flow in both general and local circulation (including the renal circulation) is the renin-angiotensinaldosterone system (RAAS ...
Natalia Butt-Hussaim, Jacek Manitius
doaj   +1 more source

Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]

open access: yes, 2010
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Muller, DN   +38 more
core   +1 more source

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