Results 11 to 20 of about 18,284,607 (258)
Renin-angiotensin system revisited [PDF]
Journal of Internal Medicine, 2008 Abstract.New components and functions of the renin‐angiotensin system (RAS) are still being unravelled. The classical RAS as it looked in the middle 1970s consisted of circulating renin, acting on angiotensinogen to produce angiotensin I, which in turn was converted into angiotensin II (Ang II) by angiotensin‐converting enzyme (ACE).
F Fyhrquist
exaly +3 more sources
The vascular renin-angiotensin-aldosterone system [PDF]
, 2001 PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
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Renin-Angiotensin System [PDF]
Archives of Andrology, 1988 Renin, a protease that cleaves the prohormone angiotensinogen thereby releasing angiotensin I, plays a major role in regulating blood pressure and electrolyte balance. Although renin is synthesized mainly in the cortical cells of the kidney, the presence of renin or reninlike activity has been recognized in various extrarenal tissues of humans and ...
A, Okuyama +4 more
openaire +2 more sources
The renin-angiotensin system and malignancy [PDF]
Carcinogenesis, 2008 The renin-angiotensin system (RAS) is usually associated with its systemic action on cardiovascular homoeostasis. However, recent studies suggest that at a local tissue level, the RAS influences tumour growth. The potential of the RAS as a target for cancer treatment and the suggested underlying mechanisms of its paracrine effects are reviewed here ...
Eleanor I, Ager +2 more
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Renin-Angiotensin System [PDF]
New England Journal of Medicine, 1975 ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire +3 more sources
The renin-angiotensin-aldosterone system during haemodialysis with acetate or bicarbonate at different dialysate sodium concentrations [PDF]
, 1987 The hormones of the renin angiotensin aldosterone system were measured during regular haemodialysis with acetate or bicarbonate at dialysate sodium concentrations of 135, 140, 145, and 150 mmol/l.
Ress, K. M. +3 more
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ACE2 in the renin–angiotensin system
Clinical Science, 2020 AbstractIn 2020 we are celebrating the 20th anniversary of the angiotensin-converting enzyme 2 (ACE2) discovery. This event was a landmark that shaped the way that we see the renin–angiotensin system (RAS) today. ACE2 is an important molecular hub that connects the RAS classical arm, formed mainly by the octapeptide angiotensin II (Ang II) and its ...
Verano-Braga, Thiago +4 more
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Intrarenal renin–angiotensin system [PDF]
Molecular and Cellular Endocrinology, 2009 Phylogenetically the renin-angiotensin system (RAS) is an ancient regulatory system which has attracted the attention of researchers for about a century. As a result of their efforts, different types of RAS inhibitors are now widely used as therapeutic medicines. The scientific enthusiasm toward RAS remains undiminished and new findings and discoveries
openaire +3 more sources
Regulation of plasma aldosterone during hemodialysis [PDF]
, 1990 In order to clarify the influence of serum potassium, serum sodium and plasma angiotensin II concentrations on aldosterone release during hemodialysis (HD), six chronic hemodialysis patients were studied during HD with varying dialysate sodium ...
B.K. Krämer +9 more
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Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]
, 2010 The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Muller, DN +38 more
core +1 more source