Results 11 to 20 of about 98,067 (262)
Journal of Pharmacological Sciences, 2010 Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage.
Atsuhiro Ichihara +6 more
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BMC Nephrology, 2012 Background Dual renin-angiotensin system blockade with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers has been advocated to minimize proteinuria. However, recent trials have questioned the renal safety of this approach.
Fernandez-Fernandez Beatriz +5 more
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Nicotine and the renin-angiotensin system [PDF]
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2018 Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in constant decline since the 1950s, the introduction of e-cigarettes or electronic nicotine delivery systems 10 yr ago has attracted former smokers as well as a new generation of consumers.
Joshua M, Oakes +4 more
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The renin–angiotensin system: a possible new target for depression
BMC Medicine, 2017 Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in multiple pathways related to neurodevelopment ...
João Vian +9 more
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Intrarenal renin–angiotensin system [PDF]
Molecular and Cellular Endocrinology, 2009 Phylogenetically the renin-angiotensin system (RAS) is an ancient regulatory system which has attracted the attention of researchers for about a century. As a result of their efforts, different types of RAS inhibitors are now widely used as therapeutic medicines. The scientific enthusiasm toward RAS remains undiminished and new findings and discoveries
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Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review [PDF]
BIO Web of ConferencesOne of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation.
Capritasari Rafiastiana +2 more
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Influence of Captopril Treatment of Plasma Renin Activity � Mathematical Model
Notulae Scientia Biologicae, 2010 A model of the dynamics of plasma renin activity under the influence of various doses of captopril is formulated. The influence of captopril on renin angiotensin system is different from the effects of the other studied drugs nifedipine and nicardipine.
Kaloyan Bonchev YANKOV +1 more
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Mediators of Inflammation, 2009 Recent evidence shows that the renin-angiotensin system is a crucial player in atherosclerotic processes. The regulation of arterial blood pressure was considered from its first description of the main mechanism involved.
Fabrizio Montecucco +2 more
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Aging and the Renin-Angiotensin System [PDF]
Hypertension, 2012 Angiotensin II (Ang II), the dominant effector molecule of the renin-angiotensin system (RAS), exerts its effects on binding of 2 pharmacologically distinct rhodopsin-like G protein–associated receptors, the type 1 and the type 2 (AT1 and AT2) receptors.1 Human cells express a single AT1 receptor, whereas 2 isoforms, AT1A and AT1B with 95% of amino ...
Conti, Sara +2 more
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Pathological Role of Angiotensin II in Severe COVID-19
TH Open, 2020 The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
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