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The Journal of Clinical Hypertension, 2011 KEY POINTS AND PRACTICAL RECOMMENDATIONS: • Aliskiren, the sole oral renin inhibitor approved by the US Food and Drug Administration, is indicated for the treatment of hypertension, either as monotherapy or in combination, with reductions in blood pressure similar to other agents. • Early evidence suggests that aliskiren confers additional benefit in
Naomi D L, Fisher, Emma A, Meagher
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundGuidelines for hypertension vary in their preference for initial combination therapy or initial monotherapy, stratified by patient profile; therefore, we compared the efficacy and tolerability of these approaches.
Thomas M. MacDonald +13 more
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Furosemide stimulates renin expression in the kidneys of salt-supplemented rats [PDF]
, 1993 This study was conducted to obtain information about a possible influence of salt transport by the thick ascending limb of Henle (TALH) and the macula densa on the expression of renin in the kidney.
Eckardt, K. U. +13 more
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Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]
, 1989 The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Arendt, Rainer M. +5 more
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Reminiscences of Ervin G Erdös [PDF]
Scripta Medica, 2019 This article includes personal reminiscence of the great scientist Ervin G Erdös (1922-2019). Dr Erdös was born in Budapest, where he studied medicine. He finished his medical school in Munich, and obtained MD degree in 1952.
Igić Rajko
doaj
Disparate effects of calcium channel blockers on pressure dependence of renin secretion and flow in the isolated perfused rat kidney [PDF]
, 1992 Using the model of isolated perfused rat kidneys this study was performed to investigate whether or not voltage-operated calcium channels are essentially involved in the pressure control of renin secretion from the kidneys. At a perfusion pressure of 100
Scholz, Holger +3 more
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Role of cGMP as second messenger of adenosine in the inhibition of renin release [PDF]
, 1988 Adenosine is known to be a potent inhibitor of renin release from the kidneys. The aim of this study was to investigate the transmembrane signalling avenue that the second messenger of adenosine causes inhibition of renal renin release.
Kurtz, Armin +7 more
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Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney [PDF]
, 1993 Using isolated rat kidneys perfused at controlled pressure, we examined a potential role of endothelium-derived relaxing factor (EDRF) in the pressure control of renin secretion.
Kurtz, Armin +5 more
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Renin and Renin Inhibition in Anephric Man
Clinical and Experimental Hypertension, 1993 Renin activity appears to be present in low concentrations in the plasma of anephric humans but could be artifactual secondary to inadvertent activation of prorenin during specimen collection and handling or from a renin-like enzyme. We studied the effects of specimen collection, storage, different assay conditions, trypsin activation, and the renin ...
J A, Opsahl +4 more
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Animal, 2009 If ewes consumed a high-salt diet or saltbush during the last 3 months of pregnancy and for 3 weeks after birth, we expected the renin activity of their lamb to be suppressed at birth and at 3 weeks of age.
M.A. Chadwick +3 more
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