Results 31 to 40 of about 168,039 (206)

Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]

, 2010
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Muller, DN, Cartwright, JE, Pijnenborg, R, Pijnenborg, R., Stefan Verlohren, Staff, A.C., Luft, F.C., Mueller, D.N., Lydia Hering, Brosnihan, KB, Anne C. Staff, Berthold Huppertz, Katrin Wenzel, Wenzel, K., Brosnihan, K.B., Dechend, R, Geusens, N, Robert Pijnenborg, Herse, F, Judith E. Cartwright, Herse, F., Wenzel, K, Huppertz, B, Florian Herse, Staff, AC, Ralf Dechend, Nele Geusens, Cartwright, J.E., K. Bridget Brosnihan, Huppertz, B., Geusens, N., Hering, L, Dominik N. Muller, Dechend, R., Hering, L., Verlohren, S, Friedrich C. Luft, Verlohren, S., Luft, FC   +38 more
core   +1 more source

Kinetics of the inhibition of renin and angiotensin I-converting enzyme by cod (Gadus morhua) protein hydrolysates and their antihypertensive effects in spontaneously hypertensive rats

Food & Nutrition Research, 2015
Background: Cod muscle has a balanced protein profile that contains potentially bioactive amino acid sequences. However, there is limited information on release of these peptides from the parent proteins and their ability to modulate mammalian blood ...
Abraham T. Girgih, Ifeanyi D. Nwachukwu, Fida Hasan, Tayo N. Fagbemi, Tom Gill, Rotimi E. Aluko   +5 more
doaj   +1 more source

The evolutionary development of the renin angiotensin aldosterone system and its importance for the survival of the human species

Arterial Hypertension, 2021
Kidneys produce a number of substances that affect intrarenal blood circulation; however, the key system that regulates blood flow in both general and local circulation (including the renal circulation) is the renin-angiotensinaldosterone system (RAAS ...
Natalia Butt-Hussaim, Jacek Manitius
doaj   +1 more source

Relation of the renin–angiotensin–aldosterone system with potential cardiac injury and remodelling: the SABPA study

Blood Pressure, 2020
Purpose: The renin-angiotensin-aldosterone system (RAAS) plays an important role in maintaining hemodynamic homeostasis. Ethnic disparities exist regarding RAAS activity due to sympathetic activity and sodium-water retention, however the implications ...
Lebo F. Gafane-Matemane, Nametsegang L. Mokae, Yolandi Breet, Leone Malan   +3 more
doaj   +1 more source

DELETIONAL ANALYSIS OF THE HUMAN RENIN PROMOTER: TRANSCRIPTIONAL ACTIVATION BY THE SV40 ENHANCER ENABLES IDENTIFICATION OF PROMOTER REGULATORY ELEMENTS IN NON-RENIN-EXPRESSING CELLS [PDF]

, 1993
Identification of regulatory elements in the human renin gene promoter has been hindered by the lack of suitable renin-expressing cell lines. In this paper, the SV40 viral enhancer is coupled to a human renin promoter/chloramphenicol acetyltransferase ...
Noriyuki, KASAHARA
core   +1 more source

Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion

Frontiers in Pharmacology, 2019
Pharmacological inhibition of the renin–angiotensin–aldosterone system (RAAS) is, in combination with diuretics, the first-choice treatment for hypertension, although 10–20% of patients do not respond adequately.
Andrea Schramm, Frank Schweda, Maria Luisa S. Sequeira-Lopez, Franz Hofmann, Peter Sandner, Jens Schlossmann   +5 more
doaj   +1 more source

Influence of Polymorphism of Vitamin D Receptor (Fok I) on Hypertension [PDF]

Brazilian Archives of Biology and Technology, 2020
Evidence suggests that polymorphisms in the gene encoding a vitamin D receptor might affect blood pressure. The objective of this systematic review was to investigate the association between hypertension and vitamin D receptor (Fok I) gene polymorphism ...
Ivone Freires de Oliveira Costa Nunes, Flaviane Alves de Pinho, Maria do Socorro Pires e Cruz, Adriana de Azevedo Paiva, Cecilia Maria Resende Gonçalves de Carvalho   +4 more
doaj   +2 more sources

Of Mice and Renin [PDF]

Hypertension, 2017
See related article, pp 119–128 Organisms tend to compensate for the need of a cellular function by increasing the amount or the size of the responsible cell type. Hypertrophy of all muscle types under increased workload is a prominent example. Also several hormone systems react by increasing the amount of hormone-producing cells, when the main ...
openaire   +2 more sources

Major Adverse Cardiovascular Events in Primary Aldosteronism After Adrenalectomy or Mineralocorticoid Receptor Antagonist Treatment: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The object of this study was to investigate the incidence rate of major adverse cardiovascular event (MACE) among patients with primary aldosteronism (PA) after adrenalectomy or mineralocorticoid receptor antagonist (MRA) treatment.
Chien‐Wei Huang, Tse‐Ying Huang, Ya‐Fei Yang, Li‐Yang Chang, Yu‐Kang Tu, Vin‐Cent Wu, Jui‐Yi Chen   +6 more
doaj   +1 more source

Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]

, 1990
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Skott, O., Kurtz, Armin, Penner, R., Chegini, S., Kurtz, A., Skøtt, Ole, Penner R, Chegini S, Kurtz A, Skott O   +9 more
core   +1 more source