Results 31 to 40 of about 229,829 (311)
Complex Role for E‐Prostanoid 4 Receptors in Hypertension
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Prostaglandin E2 (PGE2) is a major prostanoid with multiple actions that potentially affect blood pressure (BP). PGE2 acts through 4 distinct E‐prostanoid (EP) receptor isoforms: EP1 to EP4.
Marcela Herrera +5 more
doaj +1 more source
Arterial Hypertension, 2021 Kidneys produce a number of substances that affect intrarenal blood circulation; however, the key system that regulates blood flow in both general and local circulation (including the renal circulation) is the renin-angiotensinaldosterone system (RAAS ...
Natalia Butt-Hussaim, Jacek Manitius
doaj +1 more source
Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet [PDF]
, 2017 AIM:To determine the effect of tempol in normal rats fed high salt on arterial pressure and the balance between antagonist components of the renal renin-angiotensin system.METHODS:Sprague-Dawley rats were fed with 8% NaCl high-salt (HS) or 0.4% NaCl ...
Cao, Gabriel Fernando +7 more
core +1 more source
Renin-Angiotensin System [PDF]
New England Journal of Medicine, 1975 ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire +3 more sources
Acta Medica Iranica, 1996 - Pseudohypoaldosteronism (P'HA) is referred to a state of endorgan unresponsiveness to aldosterone. In this article a 12 day - old mule newborn is presented with hyponatremia, hyperkalemia and metabolic acidosis.
A. Rabbani., B. Goharfar, A. Dehgani
doaj
Changes in renal WT-1 expression preceding hypertension development [PDF]
, 2016 Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica +8 more
core +2 more sources
Influence of Polymorphism of Vitamin D Receptor (Fok I) on Hypertension [PDF]
Brazilian Archives of Biology and Technology, 2020 Evidence suggests that polymorphisms in the gene encoding a vitamin D receptor might affect blood pressure. The objective of this systematic review was to investigate the association between hypertension and vitamin D receptor (Fok I) gene polymorphism ...
Ivone Freires de Oliveira Costa Nunes +4 more
doaj +2 more sources
Advanced Materials Technologies, EarlyView.This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source
Advanced Science, EarlyView.4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang +7 more
wiley +1 more source
Advanced Science, EarlyView.NSUN5 is downregulated in hyperuricaemic nephropathy. Overexpression of NSUN5 enhances the stability of SCD1 mRNA through the m5C reader YBX2, ultimately inhibiting ferroptosis in renal tubular epithelial cells. Additionally, this axis suppresses the NF‐κB signaling pathway to alleviate inflammation and upregulates ABCG2 to promote uric acid excretion,
Xiu‐xiu Song +12 more
wiley +1 more source