Results 41 to 50 of about 39,387 (167)

Disparate effects of calcium channel blockers on pressure dependence of renin secretion and flow in the isolated perfused rat kidney

, 1992
Using the model of isolated perfused rat kidneys this study was performed to investigate whether or not voltage-operated calcium channels are essentially involved in the pressure control of renin secretion from the kidneys. At a perfusion pressure of 100
Scholz, Holger, Kurtz, Armin
core   +1 more source

Protective Effects of Nanoparticle-Loaded Aliskiren on Cardiovascular System in Spontaneously Hypertensive Rats

Molecules, 2019
Aliskiren, a renin inhibitor, has been shown to have cardioprotective and blood pressure (BP) lowering effects. We aimed to determine the effects of nanoparticle-loaded aliskiren on BP, nitric oxide synthase activity (NOS) and structural alterations of ...
Olga Pechanova, Andrej Barta, Martina Koneracka, Vlasta Zavisova, Martina Kubovcikova, Jana Klimentova, Jozef Tӧrӧk, Anna Zemancikova, Martina Cebova   +8 more
doaj   +1 more source

Concurrent Primary Aldosteronism and Renal Artery Stenosis: An Overlooked Condition Inducing Resistant Hypertension

Frontiers in Cardiovascular Medicine, 2022
To explore the clinical features of coexisting primary aldosteronism (PA) and renal artery stenosis (RAS), we retrospectively analyzed records from 71 patients with PA with RAS and a control group of 121 patients with PA without RAS. Aldosterone-to-renin
Lin Zhao, Jinhong Xue, Yi Zhou, Xueqi Dong, Fang Luo, Xiongjing Jiang, Xinping Du, Xianliang Zhou, Xu Meng   +8 more
doaj   +1 more source

Hormonal and hemodynamic changes in middle-aged urban residents with obesity depending on blood pressure

Mìžnarodnij Endokrinologìčnij Žurnal, 2020
Background. The relevance of the study is due to the significant spread of overweight of varying severity among the population and a significant risk of developing comorbid pathological conditions, including arterial hypertension (AH).
E.V. Misyura, T.I. Yefimenko, I.P. Dunaieva   +2 more
doaj   +1 more source

Angiotensinogen and the Modulation of Blood Pressure

Frontiers in Cardiovascular Medicine, 2021
The angiotensin peptides that control blood pressure are released from the non-inhibitory plasma serpin, angiotensinogen, on cleavage of its extended N-terminal tail by the specific aspartyl-protease, renin. Angiotensinogen had previously been assumed to
Zimei Shu, Jiahui Wan, Randy J. Read, Robin W. Carrell, Aiwu Zhou   +4 more
doaj   +1 more source

Показатели вариабельности ритма сердца, активности ренина и содержания альдостерона в плазме крови при ренопаренхиматозной артериальной гипертензии

Архивъ внутренней медицины, 2011
In the pathogenesis of renal arterial hypertension an important role of the renin-angiotensin-aldosterone (RAAS) is confirmed. In addition to the humoral effects of the RAAS and blood pressure actively controls the vegetative nervous system (VNS ...
Н. Ю. Боровкова, Н. Н. Боровков, Е. О. Обухова, Ю. А. Хорькина, М. П. Нистратова, Б. Н. Сиднев, М. Ю. Серопян   +6 more
doaj   +1 more source

Effect of the renin inhibitor aliskiren against retinal ischemia-reperfusion injury [PDF]

, 2015
香川大学Kagawa University博士（医学）Abstract The purpose of this study was to investigate the effect of the renin inhibitor, aliskiren, on retinal ischemia-reperfusion injury. Retinal ischemia was induced by increasing intraocular pressure to 130 mmHg.
請川, 香里, ウケガワ, カオリ, Ukegawa, Kaori   +2 more
core   +1 more source

Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia

Бюллетень сибирской медицины, 2011
The association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied.
O. V. Radkov, M. N. Kalinkin, V. V. Zavarin   +2 more
doaj   +1 more source

Angiotensinogen and C3 compete for renin-induced complement activation

Frontiers in Immunology
Renin from plasma, kidney, and recombinant sources was previously demonstrated to cleave C3 to C3a and C3b. C3a was generated at a similar rate to that by C3 convertase, and C3 cleavage was inhibited by the renin inhibitor aliskiren.
Ann-Charlotte Kristoffersson, Albin Sköld, Charlotte Welinder, Markus Wendler, Gabriella Kalliokoski, Zivile Bekassy, Diana Karpman   +6 more
doaj   +1 more source

EVOLUTION STAGES OF LOW RENIN HYPERTENSION

Рациональная фармакотерапия в кардиологии, 2016
Aim. To find out similarities and differences between various evolutionary stages of low rennin hypertension (LRHT), and to develop its diagnostic criteria.Material and methods.
S. V. Akhadov, G. R. Ruzbanova, G. S. Molchanovа   +2 more
doaj   +1 more source