Results 61 to 70 of about 39,387 (167)

DELETIONAL ANALYSIS OF THE HUMAN RENIN PROMOTER: TRANSCRIPTIONAL ACTIVATION BY THE SV40 ENHANCER ENABLES IDENTIFICATION OF PROMOTER REGULATORY ELEMENTS IN NON-RENIN-EXPRESSING CELLS

, 1993
Identification of regulatory elements in the human renin gene promoter has been hindered by the lack of suitable renin-expressing cell lines. In this paper, the SV40 viral enhancer is coupled to a human renin promoter/chloramphenicol acetyltransferase ...
Noriyuki, KASAHARA
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Predicted Release and Analysis of Novel ACE-I, Renin, and DPP-IV Inhibitory Peptides from Common Oat (Avena sativa) Protein Hydrolysates Using in Silico Analysis

Foods, 2017
The renin-angiotensin-aldosterone system (RAAS) plays an important role in regulating hypertension by controlling vasoconstriction and intravascular fluid volume. RAAS itself is largely regulated by the actions of renin (EC 3.4.23.15) and the angiotensin-
Stephen Bleakley, Maria Hayes, Nora O’ Shea, Eimear Gallagher, Tomas Lafarga   +4 more
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Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study

, 2009
Introduction. This study addressed the role of the local renin-angiotensin system (RAS) in the left ventriular hypertropy (LVH) induced by swimming training using pharmacological blockade. Materials and methods.
CERENCIO, Marcela, OLIVEIRA, Edilamar M., KRIEGER, Jose E., SASAKI, Mauricio S., BARAUNA, Valerio G.   +4 more
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Renin-angiotensin system overactivation in polycystic ovary syndrome, a risk for SARS-CoV-2 infection?

, 2021
Background: The SARS-CoV-2 coronavirus gains entry to target cells via the angiotensin-converting enzyme 2 (ACE2) receptor present on cells in blood vessels, lungs, heart, intestines, and kidneys. Renin-Angiotensin System (RAS) overactivity has also been
Abu Saleh Md Moin (6189512), Stephen Atkin (12597178), Alexandra E Butler (4375915), Thozhukat Sathyapalan (704787)   +3 more
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Metabolic Syndrome Nonalcoholic Steatohepatitis Male Mouse With Adeno‐Associated Viral Renin as a Novel Model for Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Heart failure with preserved ejection fraction (HFpEF) currently accounts for more than half of patients with HF, with limited approved evidence‐based therapies.
Yuji Shi, Patricia Perez‐Bonilla, Xian Chen, Kelly Tam, Mackenzie Marshall, Jeffrey Morin, Brianna LaViolette, Nouaying R. Kue, Federico Damilano, Russell A. Miller, Bei B. Zhang, Rachel J. Roth Flach, Dinesh Hirenallur‐Shanthappa   +12 more
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Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy.

, 2010
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Muller, DN, Cartwright, JE, Pijnenborg, R, Pijnenborg, R., Stefan Verlohren, Staff, A.C., Luft, F.C., Mueller, D.N., Lydia Hering, Brosnihan, KB, Anne C. Staff, Berthold Huppertz, Katrin Wenzel, Wenzel, K., Brosnihan, K.B., Dechend, R, Geusens, N, Robert Pijnenborg, Herse, F, Judith E. Cartwright, Herse, F., Wenzel, K, Huppertz, B, Florian Herse, Staff, AC, Ralf Dechend, Nele Geusens, Cartwright, J.E., K. Bridget Brosnihan, Huppertz, B., Geusens, N., Hering, L, Dominik N. Muller, Dechend, R., Hering, L., Verlohren, S, Friedrich C. Luft, Verlohren, S., Luft, FC   +38 more
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Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundGuidelines for hypertension vary in their preference for initial combination therapy or initial monotherapy, stratified by patient profile; therefore, we compared the efficacy and tolerability of these approaches.
Thomas M. MacDonald, Bryan Williams, David J. Webb, Steve Morant, Mark Caulfield, J. Kennedy Cruickshank, Ian Ford, Peter Sever, Isla S. Mackenzie, Sandosh Padmanabhan, Gerald P. McCann, Jackie Salsbury, Gordon McInnes, Morris J. Brown   +13 more
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Local Hematopoietic Renin-Angiotensin System in Myeloid Versus Lymphoid Hematological Neoplastic Disorders

, 2013
There is preliminary evidence that the local renin-angiotensin system (RAS) could affect neoplastic hematopoiesis. The aim of this study is to search messenger RNA (mRNA) expressions of the essential RAS elements in myeloid and lymphoid hematological ...
Sayinalp, Nilgun, Goker, Hakan, Ng, Ozden Hatirnaz, Aksu, Salih, Haznedaroglu, Ibrahim C., Buyukasik, Yahya, Tatonyan, Suzin Catal, Ozcebe, Osman I., ÖZCEBE, OSMAN İLHAMİ, Erbilgin, Yucel, Ozbek, Ugur, Uz, Burak, Sayitoglu, Muge   +12 more
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Renin inhibitors are a new direction in the treatment of arterial hypertension

Терапевтический архив, 2010
The paper covers current problems in the treatment of arterial hypertension. Renin is an important and promising therapeutic target. The direct renin inhibitor aliskiren (Rasilez) is a promising current effective antihypertensive agent that has cardio ...
Yuriy Aleksandrovich Vasyuk, Irina Akhmedkhanovna Sadulaeva, Elena Nikolaevna Yushchuk, Ol'ga Sergeevna Trofimenko, Mikhail Vasil'evich Chirkov, Viktoriya Sergeevna Fedoseeva, Kirill Georgievich Kulikov, Yu A Vasyuk, I A Sadulayeva, E N Yushchuk, O S Trofimenko, M V Chirkov, V S Fedoseyeva, K G Kulikov   +13 more
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Reminiscences of Ervin G Erdös [PDF]

Scripta Medica, 2019
This article includes personal reminiscence of the great scientist Ervin G Erdös (1922-2019). Dr Erdös was born in Budapest, where he studied medicine. He finished his medical school in Munich, and obtained MD degree in 1952.
Igić Rajko
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