Results 1 to 10 of about 756,250 (282)
Renin and 1-year mortality in critically ill patients with ARDS: trajectories, discrimination, and survival analysis [PDF]
Frontiers in MedicineBackgroundWe investigated whether early and serial plasma renin concentration (PRC) is associated with 1-year mortality in critically ill patients with COVID-19-related acute respiratory distress syndrome (ARDS).MethodsWe conducted a single-center ...
Gabriele Melegari +10 more
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Therapeutic Implications of Renin–Angiotensin System Modulators in Alzheimer’s Dementia
Pharmaceutics, 2023 The Renin–Angiotensin System (RAS) has attracted considerable interest beyond its traditional cardiovascular role due to emerging data indicating its potential involvement in neurodegenerative diseases, including Alzheimer’s dementia (AD).
Daniela-Carmen Ababei +8 more
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Advanced Medical Journal, 2023 Background and objectives: Hypertension is an important cardiovascular disease that carries a high rate of mortality and morbidity if not controlled. Significant complications of untreated hypertension include vascular atherosclerosis, chronic kidney ...
Mohammed Hasan Almeshhadani +3 more
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Development of a novel murine heart failure model overexpressing human renin and angiotensinogen
FEBS Open Bio, 2020 Renin is the rate‐limiting enzyme of the renin–angiotensin system cascade, which drives the pathophysiological progression of heart failure. Species differences in the amino acid sequence of the catalytic domain of renin limit evaluations of the potency ...
Tomoya Hara +6 more
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Cells, 2020 The article describes the rationale for inhibition of the renin-angiotensin system (RAS) pathways as specific targets in patients infected by SARS-CoV-2 in order to prevent positive feedback-loop mechanisms.
Loris Zamai
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The renin‐angiotensin‐aldosterone system, neurohumoral axis and cardiovascular mortality in LURIC
The Journal of Clinical Hypertension, 2022 Although neurohormones and Renin‐Angiotensin‐Aldosterone‐System (RAAS) components are important predictors of cardiovascular mortality (CVM), their importance for predicting outcomes in patients with/without RAAS‐blockers and different degrees of ...
Babak Yazdani +9 more
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Angiotensin-Converting Enzyme Inhibitors and Adipokines: The Role of Visfatin and Apelin in Cardiovascular Disease Management [PDF]
المجلة العراقية للصيدلة, 2023 Background: Angiotensin-converting enzyme (ACE) Inhibitors are medications pivotal in cardiovascular disease management, impacting the renin-angiotensin system which plays a critical role in cardiovascular health. These inhibitors not only modulate blood
Yaseen Jumaah +2 more
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The Use of Renin-Angiotensin System Blockades Among Patients with Chronic Kidney Disease
Advanced Medical Journal, 2023 Background and objectives: Hypertension is common in adult patients with chronic kidney disease with a prevalence that depends on the stage and etiology of chronic kidney disease and has been reported to range from 60-90%.
Majeed Hassan Shekhany
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Journal of Pharmacological Sciences, 2010 Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage.
Atsuhiro Ichihara +6 more
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Кардиоваскулярная терапия и профилактика, 2011 In the 1970s, pharmacological therapy interrupting the renin-angiotensin system was considered beneficial for patients with high-renin hypertension. Angiotensin-converting enzyme (ACE) inhibitors proved to be effective not only in patients with high ...
C. Napoli
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