Results 11 to 20 of about 756,250 (282)
Hyperkalemia and Renin–Angiotensin–Aldosterone System Inhibitors Dose Therapy in Heart Failure With Reduced Ejection Fraction [PDF]
Cardiac Failure Review, 2019 Renin–angiotensin–aldosterone system inhibitors (RAASi) are known to improve outcomes in patients who have heart failure with reduced ejection fraction (HFrEF).
Giuseppe MC Rosano +3 more
doaj +2 more sources
Vascular Health and Risk Management, 2008 Kristina AllikmetsDepartment of Drug Development and Medical Affairs, Nycomed Group, Roskilde, DenmarkAbstract: The importance of renin-angiotensin-aldosterone system (RAAS) in diseases such as hypertension, congestive heart failure and chronic renal ...
Kristina Allikmets
doaj +1 more source
Vascular Health and Risk Management, 2008 Kalathil K SureshkumarDivision of Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, Pennsylvania, USAAbstract: Hypertension is a major risk factor for the development of cardiovascular and renal disease.
Kalathil K Sureshkumar
doaj +1 more source
J Clin Hypertens (Greenwich), 2011 KEY POINTS AND PRACTICAL RECOMMENDATIONS: • Aliskiren, the sole oral renin inhibitor approved by the US Food and Drug Administration, is indicated for the treatment of hypertension, either as monotherapy or in combination, with reductions in blood pressure similar to other agents. • Early evidence suggests that aliskiren confers additional benefit in
Fisher ND, Meagher EA.
europepmc +7 more sources
The vascular renin-angiotensin-aldosterone system [PDF]
, 2001 PhDThe renin-angiotensin-aldosterone system (RAAS) is one of the major regulators of blood pressure. The actions and generation of RAAS components at the tissue level are less well appreciated.
Xiao, Fang
core +4 more sources
Calmodulin antagonists stimulate renin secretion and inhibit renin synthesis in vitro [PDF]
, 1992 To find out whether calmodulin activity could be a common denominator for the cellular control of renin secretion and synthesis, we have examined the effects of calmodulin antagonists on the secretion and the synthesis of renin in primary cultures of ...
Kurtz, Armin +12 more
core +1 more source
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney [PDF]
, 1993 Using isolated rat kidneys perfused at controlled pressure, we examined a potential role of endothelium-derived relaxing factor (EDRF) in the pressure control of renin secretion.
Kurtz, Armin +5 more
core +1 more source
The renin-angiotensin-aldosterone system during haemodialysis with acetate or bicarbonate at different dialysate sodium concentrations [PDF]
, 1987 The hormones of the renin angiotensin aldosterone system were measured during regular haemodialysis with acetate or bicarbonate at dialysate sodium concentrations of 135, 140, 145, and 150 mmol/l.
Ress, K. M. +3 more
core +1 more source
JCI Insight, 2021 Inhibitors of the renin-angiotensin system (RAS) are widely used to treat hypertension. Using mice harboring fluorescent cell lineage tracers, single-cell RNA-Seq, and long-term inhibition of RAS in both mice and humans, we found that deletion of renin ...
Hirofumi Watanabe +9 more
doaj +1 more source
Aliskiren: An orally active renin inhibitor
Journal of Pharmacy and Bioallied Sciences, 2011 Renin inhibitors are antihypertensive drugs that block the first step in the renin-angiotensin system. Their mechanism of action differs from that of the angiotensin-converting enzyme inhibitors and angiotensin-receptor antagonists, but like these drugs,
Pranay Wal +3 more
doaj +1 more source