Results 1 to 10 of about 161,997 (305)
Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure [PDF]
ESC Heart Failure, 2020 Aims Activation of the renin–angiotensin–aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Masatake Kobayashi +17 more
doaj +6 more sources
Dietary Sodium Reduction Reveals Aldosterone Dysregulation in Patients With Essential Hypertension [PDF]
The Journal of Clinical HypertensionDietary sodium reduction affects blood pressure (BP), the renin‐angiotensin‐aldosterone system (RAAS) and natriuretic peptides. Whether baseline levels of these hormones impact BP response to sodium reduction remains unknown.
Camilla L. Duus +4 more
doaj +2 more sources
Relationship between blood pressure level and activity of renin-aldosterone axis in patients with essential hypertension—a retrospective study [PDF]
PeerJBackground A study indicates that elevated aldosterone levels increase the risk of hypertension by 16%. This retrospective cohort study examines the relationship between blood pressure and renin-aldosterone levels in patients with essential hypertension (
Peijuan Li +5 more
doaj +3 more sources
Aldosterone is a possible new stimulating factor for promoting vascular calcification
Frontiers in Bioscience-Landmark, 2021 Background: Aldosterone is an important hormone in the renin-angiotensin-aldosterone system (RAAS), and playing a pivotal role in the development of hypertension, heart failure, and other cardiovascular diseases.
Xusheng Zhang +6 more
doaj +1 more source
Frontiers in Endocrinology, 2023 Aldosterone is one of the most essential hormones synthesized by the adrenal gland because it regulates water and electrolyte balance. G protein–coupled estrogen receptor (GPER) is a newly discovered aldosterone receptor, which is proposed to mediate the
Xuehan Li +11 more
doaj +1 more source
Prague Medical Report, 2021 Determination of renin plasma levels is useful in the diagnosis of hypertension and in the therapeutic follow-up of hypertensive patients. Plasmatic concentration of renin decreases in patients with hypertension due to a primary hyperaldosteronism ...
Jana Uhrová +3 more
doaj +1 more source
Cells, 2020 Aldosterone indirectly regulates water reabsorption in the distal tubule by regulating sodium reabsorption. However, the direct effect of aldosterone on vasopressin-regulated water and urea permeability in the rat inner medullary collecting duct (IMCD ...
Yanhua Wang +4 more
doaj +1 more source
Pathology and gene mutations of aldosterone-producing lesions
Endocrine Journal, 2023 The human adrenal cortex secretes aldosterone and cortisol as major corticosteroids. For their production, CYP11B2 and CYP11B1 catalyze the last steps in the syntheses of aldosterone and cortisol, respectively.
Koshiro Nishimoto +4 more
doaj +1 more source
Biomedicines, 2021 Aldosterone excess plays a major role in the progression of cardiac dysfunction and remodeling in clinical diseases such as primary aldosteronism and heart failure. However, the effect of aldosterone excess on cardiac mitochondria is unclear.
Cheng-Hsuan Tsai +12 more
doaj +1 more source
Frontiers in Physiology, 2022 Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na+ reabsorption via the epithelial Na+ channel (ENaC) and the NaCl cotransporter (NCC).
Mathias Kristensen +2 more
doaj +1 more source