Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans. [PDF]
PLoS ONE, 2014 Patients with primary aldosteronism are associated with increased myocardial fibrosis. Galectin-3 is one of the most important mediators between macrophage activation and myocardial fibrosis.To investigate whether aldosterone induces galectin-3 secretion
Yen-Hung Lin +11 more
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Frontiers in Endocrinology, 2021 Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension. It can be caused by the overproduction of aldosterone in one or both adrenal glands. The most common subtypes of PA are unilateral aldosterone over-production
Fatin Athirah Pauzi, Elena Aisha Azizan
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Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]
, 2009 <b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C. +8 more
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Body mass index predicts aldosterone production in hypertensive postmenopausal women
Clinical and Experimental Hypertension, 2020 Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic. Related works have shown exciting results on the effects of various conditions on aldosterone content, but the correlation between ...
Lijun Li +3 more
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Nongenomic effects of aldosterone on phosphocreatine levels in human calf muscle during recovery from exercise. [PDF]
, 1996 Nongenomic in vitro effects of aldosterone on the sodium-proton antiport and intracellular second messengers have been described in human mononuclear leukocytes, vascular smooth muscle cells, and endothelial cells.
Gerzer, Rupert +4 more
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The associations of adipokines with selected markers of the renin-angiotensinogen-aldosterone system: the multi-ethnic study of atherosclerosis. [PDF]
, 2015 Among obese individuals, increased sympathetic nervous system (SNS) activity results in increased renin and aldosterone production, as well as renal tubular sodium reabsorption.
Allison, MA +4 more
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Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]
, 1989 The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Anderson +46 more
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Effect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells
Kidney Research and Clinical Practice, 2015 Background: Peritoneal fibrosis is one of the major causes of technical failure in patients on peritoneal dialysis. Epithelial-to-mesenchymal transition (EMT) of the peritoneum is an early and reversible mechanism of peritoneal fibrosis. Human peritoneal
Mina Yu +6 more
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Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis [PDF]
, 2017 Aims: We questioned whether aldosterone and oxidative stress play a role in vascular damage in severe hypertension and investigated the role of Nox1 in this process.
Ceravolo, Graziela +7 more
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Relationship between aldosterone and the metabolic syndrome in patients with obstructive sleep apnea hypopnea syndrome: effect of continuous positive airway pressure treatment. [PDF]
PLoS ONE, 2014 BACKGROUND: Metabolic syndrome (MS) occurs frequently in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). We hypothesized that aldosterone levels are elevated in OSAHS and associated with the presence of MS.
Antonia Barceló +9 more
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