Results 21 to 30 of about 123,346 (302)

Aldosterone Excess Induced Mitochondria Decrease and Dysfunction via Mineralocorticoid Receptor and Oxidative Stress In Vitro and In Vivo

open access: yesBiomedicines, 2021
Aldosterone excess plays a major role in the progression of cardiac dysfunction and remodeling in clinical diseases such as primary aldosteronism and heart failure. However, the effect of aldosterone excess on cardiac mitochondria is unclear.
Cheng-Hsuan Tsai   +12 more
doaj   +1 more source

Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humans. [PDF]

open access: yesPLoS ONE, 2014
Patients with primary aldosteronism are associated with increased myocardial fibrosis. Galectin-3 is one of the most important mediators between macrophage activation and myocardial fibrosis.To investigate whether aldosterone induces galectin-3 secretion
Yen-Hung Lin   +11 more
doaj   +1 more source

Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension

open access: yesFrontiers in Endocrinology, 2021
Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension. It can be caused by the overproduction of aldosterone in one or both adrenal glands. The most common subtypes of PA are unilateral aldosterone over-production
Fatin Athirah Pauzi, Elena Aisha Azizan
doaj   +1 more source

The renin-angiotensin-aldosterone system during haemodialysis with acetate or bicarbonate at different dialysate sodium concentrations [PDF]

open access: yes, 1987
The hormones of the renin angiotensin aldosterone system were measured during regular haemodialysis with acetate or bicarbonate at dialysate sodium concentrations of 135, 140, 145, and 150 mmol/l.
Ress, K. M.   +3 more
core   +1 more source

Regulation of plasma aldosterone during hemodialysis [PDF]

open access: yes, 1990
In order to clarify the influence of serum potassium, serum sodium and plasma angiotensin II concentrations on aldosterone release during hemodialysis (HD), six chronic hemodialysis patients were studied during HD with varying dialysate sodium ...
B.K. Krämer   +9 more
core   +1 more source

Body mass index predicts aldosterone production in hypertensive postmenopausal women

open access: yesClinical and Experimental Hypertension, 2020
Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic. Related works have shown exciting results on the effects of various conditions on aldosterone content, but the correlation between ...
Lijun Li   +3 more
doaj   +1 more source

The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]

open access: yes, 1993
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Wehling, Martin   +5 more
core   +1 more source

Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na+ Channel and the NaCl Cotransporter

open access: yesFrontiers in Physiology, 2022
Primary hyperaldosteronism (PA) is characterized by aldosterone excess and hypertension. This may be linked to increased renal Na+ reabsorption via the epithelial Na+ channel (ENaC) and the NaCl cotransporter (NCC).
Mathias Kristensen   +2 more
doaj   +1 more source

ALDOSTERONE

open access: yesAdvances in Physiology Education, 2002
Aldosterone plays a pivotal role in electrolyte and fluid homeostasis and thus control of blood pressure. The “classical” view of aldosterone action is that it targets epithelia of the distal colon and renal nephron to stimulate Na+(re)absorption and K+secretion.
Rachell E, Booth   +2 more
openaire   +2 more sources

Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]

open access: yes, 2009
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Freel, E.M.   +8 more
core   +1 more source

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