Results 361 to 370 of about 230,682 (392)
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Journal of Steroid Biochemistry, 1981
Abstract In the presence of dilute alkali aldosterone undergoes rearrangement to form an isomeric substance which is shown to be 11β, 18:18,21-diepoxy-20,21-dihydroxy-4-pregnen-3-one. The rearrangement is considered to include a tautomeric change of the side chain to produce a 20-hydroxy-21-aldehyde group which reacts with the C-18 hydroxyl group to ...
Vernon R. Mattox +2 more
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Abstract In the presence of dilute alkali aldosterone undergoes rearrangement to form an isomeric substance which is shown to be 11β, 18:18,21-diepoxy-20,21-dihydroxy-4-pregnen-3-one. The rearrangement is considered to include a tautomeric change of the side chain to produce a 20-hydroxy-21-aldehyde group which reacts with the C-18 hydroxyl group to ...
Vernon R. Mattox +2 more
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Endocrine Research, 1998
Plasma aldosterone levels were measured in adults whose body mass index ranged from lean to obese. Blood was drawn while subjects rested supine for 30-90 minutes. Aldosterone was higher in obese subjects, but could not be explained by renin or K+. The best predictors of plasma aldosterone were abdominal obesity measured as waist/hip ratio or by CT scan,
Brent M. Egan +2 more
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Plasma aldosterone levels were measured in adults whose body mass index ranged from lean to obese. Blood was drawn while subjects rested supine for 30-90 minutes. Aldosterone was higher in obese subjects, but could not be explained by renin or K+. The best predictors of plasma aldosterone were abdominal obesity measured as waist/hip ratio or by CT scan,
Brent M. Egan +2 more
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Trends in Endocrinology & Metabolism, 2000
Classically, aldosterone is a steroid hormone secreted from the adrenal cortex, which acts on kidney, colon and sweat/salivary glands to promote unidirectional sodium transport. Currently, there is excellent experimental evidence for aldosterone acting directly on the central nervous system to raise blood pressure, and on the heart to cause cardiac ...
Morag J. Young, John W. Funder
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Classically, aldosterone is a steroid hormone secreted from the adrenal cortex, which acts on kidney, colon and sweat/salivary glands to promote unidirectional sodium transport. Currently, there is excellent experimental evidence for aldosterone acting directly on the central nervous system to raise blood pressure, and on the heart to cause cardiac ...
Morag J. Young, John W. Funder
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ALDOSTERONE AND THE CIRCULATION
Australasian Annals of Medicine, 1962SummaryStudies have been made in Sheffield on volunteers placed on a dietary regime inducing sodium depletion, in order to observe the effect of alteration in the volume of the body fluid compartments on the measured output of aldosterone in the urine. Fluid volumes decreased during sodium depletion. Subsequent treatment with vasopressin injections and
C. H. Stuart-Harris +3 more
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Regulation of aldosterone synthesis and secretion.
Comprehensive Physiology, 2014Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium homeostasis, thereby helping to control blood volume and blood pressure ...
W. Bollag
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The biosynthesis of aldosterone
The Journal of Steroid Biochemistry and Molecular Biology, 1991The cellular mechanisms for aldosterone biosynthesis are incompletely understood. Although the enzymes involved are now well characterized, the dynamics of aldosterone secretion in a variety of rat adrenal preparations are not consistent with the concept that freshly synthesized corticosterone is an important intermediate.
R. Teja +4 more
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ALDOSTERONISM AND SPIRONOLACTONE
Annals of Internal Medicine, 1969Excerpt To the Editor:I was very interested in the article entitled "Aldosteronism in Hypertension: The Response to Spironolactone" by Spark and Melby (Ann. Intern. Med. 69: 685, 1968).
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2019
The prominence of obesity in the clinical population as well as the strong association of cardiovascular risk factors with obesity has prompted the investigation of the adipose tissue and its physiological contribution to cardiovascular health. A notable finding in these investigations was the discovery of the adipocyte-derived hormone leptin.
Jessica L. Faulkner +1 more
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The prominence of obesity in the clinical population as well as the strong association of cardiovascular risk factors with obesity has prompted the investigation of the adipose tissue and its physiological contribution to cardiovascular health. A notable finding in these investigations was the discovery of the adipocyte-derived hormone leptin.
Jessica L. Faulkner +1 more
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