Results 171 to 180 of about 14,491 (226)

Postoperative adjuvant therapy for driver gene-positive non-small-cell lung cancer patients. [PDF]

open access: yesChin Med J (Engl)
Lung Cancer Treatment Collaboration Group   +1 more
europepmc   +1 more source

Lung Adenocarcinoma Expressing an EML4-ALK Fusion Transcript With Premature Stop Codons and Response to Alectinib: A Case Report. [PDF]

open access: yesThorac Cancer
Ozaki M   +11 more
europepmc   +1 more source

Weight, BSA, Toxicity, and Efficacy of Tyrosine Kinase Inhibitors for <i>ALK-</i>Mutated NSCLC. [PDF]

open access: yesJTO Clin Res Rep
Munarriz BJ   +12 more
europepmc   +1 more source

Body weight gain associated with alectinib in patients with ALK+ non-small cell lung cancer: pooled analysis of individual patient data from 4 prospective clinical trials [PDF]

open access: yes
Baart, Sara   +7 more
core  

Alectinib

Reactions Weekly, 2018
Alectinib is an ATP-competitive small molecule and a second-generation inhibitor of ALK. EML4-ALK rearrangement is found in 3-5% of patients with NSCLC. The first-generation inhibitor crizotinib has changed the treatment dramatically, though most of the patients show disease progression within one year.
Herden, Marie, Waller, Cornelius
  +8 more sources

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